Refinement and Testing of Interventions to Sustain ADHD Treatment Effects Across Settings and Developmental Transitions (R34 Clinical Trial Required)

Funding Opportunity RFA-MH-20-100 from the NIH Guide for Grants and Contracts. NIMH seeks applications for pilot projects to evaluate the preliminary effectiveness of augmented or modified interventions designed to promote sustained improvement in attention-deficit/hyperactivity disorder (ADHD) symptoms and functional impairments across settings and transitions in children, adolescents, and young adults. An emphasis is placed on trials that go beyond seeking incremental gains in intervention effects, and instead take a theory-driven, empirical approach to applying modifications that will have a significant and enduring impact on functioning. In this pilot phase of effectiveness research, the trial should be designed to evaluate the feasibility, tolerability, acceptability, safety, and potential effectiveness of the approach; to address whether the intervention engages the target mechanism(s) presumed to underlie the intervention effects; and to obtain necessary preliminary data as a pre-requisite to a larger-scale, definitive effectiveness trial.
Source: NIH Funding Opportunities (Notices, PA, RFA) - Category: Research Source Type: funding

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Omega-3 fish oil supplements improve attention and vigilance in young people with attention-deficit hyperactivity disorder, who have low levels of omega-3, a study in  Translational Psychiatry suggests.
Source: The Pharmaceutical Journal - Category: Drugs & Pharmacology Source Type: research
It doesn ’t take long for a kid to check out. Or to decide you’re just another useless therapist they’re forced to see. Especially if they have attention-deficit/hyperactivity disorder (ADHD) and have been treated like they’re a bad kid often enough to begin to believe it.
Source: Journal of the American Academy of Child and Adolescent Psychiatry - Category: Psychiatry Authors: Tags: Book forum Source Type: research
Omega-3 fish oil supplements can improve attention in children with attention deficit hyperactivity disorder (ADHD) just as much as drug treatments, but only in those whose blood levels of omega-3 are low, trial results showed on Wednesday.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
AbstractPrevalence rates of attention-deficit/hyperactivity disorder (ADHD) differ with geographical areas varying in sunlight intensity. Sun- or daylight reaching the retina establishes entrainment of the circadian clock to daylight. Changes herein, hence, alterations in clock alignment, could be reflected indirectly in inattention via sleep duration. We here studied (1) annual variation in inattention at treatment initiation; (2) annual variation in response to ADHD treatment [methylphenidate (MPH)] by day of treatment initiation; and (3) dose dependence. We predicted least baseline inattention during a period of high su...
Source: European Child and Adolescent Psychiatry - Category: Psychiatry Source Type: research
Translational Psychiatry, Published online: 20 November 2019; doi:10.1038/s41398-019-0633-0High-dose eicosapentaenoic acid (EPA) improves attention and vigilance in children and adolescents with attention deficit hyperactivity disorder (ADHD) and low endogenous EPA levels
Source: Translational Psychiatry - Category: Psychiatry Authors: Source Type: research
Asking this question on behalf of a pediatric colleague. " I've been using the original Quotient ADHD test in my office for the last ten years Quotient ADHD Test The Quotient ADHD Test objectively measures hyperactivity, impulsivity and inattention to aid assessment of ADHD. The test reports micro-motion and analyzes shifts in attention state, helping to engage patients and guardians in the treatment planning process. Unfortunately, the original Quo...
Source: Student Doctor Network - Category: Universities & Medical Training Authors: Tags: Psychiatry Source Type: forums
CONCLUSION: We found no evidence that binge drinking or low alcohol intake in early pregnancy was associated with the risk of ADHD in the children. PMID: 31742728 [PubMed - as supplied by publisher]
Source: Alcoholism, Clinical and Experimental Research - Category: Addiction Authors: Tags: Alcohol Clin Exp Res Source Type: research
This study aims to advance understanding of motor coordination difficulties in children with ND-CNVs and establish relationships between intelligence quotient (IQ) and psychopathology. METHODS: 169 children with an ND-CNV (67% male, median age = 8.88 years, range 6.02-14.81) and 72 closest-in-age unaffected siblings (controls; 55% male, median age = 10.41 years, s.d. = 3.04, range 5.89-14.75) were assessed with the Developmental Coordination Disorder Questionnaire, alongside psychiatric interviews and standardised assessments of IQ. RESULTS: The children with ND-CNVs had poorer coordination ability (b = 28.98, p
Source: Psychological Medicine - Category: Psychiatry Authors: Tags: Psychol Med Source Type: research
Publication date: Available online 15 November 2019Source: Journal of Chemical NeuroanatomyAuthor(s): Amir Raoofi, Abass Aliaghaei, Mohammad-Amin Abdollahifar, Mahdi Eskandarian Boroujeni, Sara Sadat javadinia, Hadi Atabati, Beheshteh AbouhamzehAbstractBackground and AimStated in previous studies, physicians are typically prescribing methylphenidate (MPH), commonly known as Ritalin, for children diagnosed with attention deficit hyperactivity disorder (ADHD). Nevertheless, researchers have not still understood mechanisms of this stimulant medication. Research has also found an association between apoptosis signaling pathway...
Source: Journal of Chemical Neuroanatomy - Category: Neuroscience Source Type: research
While recreational marijuana is legal in 11 states as of November 2019, more states gravitating toward legalizing the recreational use of the substance, and 33 states allowing medical marijuana, there’s apparently no stopping this trend. Cannabis, in the form of marijuana, hemp, and cannabidiol (CBD)  is being used for pain relief, to alleviate stress, cope with anxiety, and a number of other mental health disorders and addictions. Yet, there’s a dearth of clinical studies that have been conducted on the overall effects on a user’s health. Clearly, as Crain’s Detroit Business points out, more ...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Medications Substance Abuse Cannabis Marijuana Source Type: blogs
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