Changes in forced oscillation technique (FOT) parameters during 4-year-follow-up in children and adolescents with asthma: possible indices for lung function decline.

Forced oscillation technique (FOT) has a potential to evaluate respiratory pathophysiology in asthma that spirometry does not detect. Since lung function decline in children with asthma has been reported to have significant impact on development of COPD in later life, we investigated changes in FOT parameters in children/adolescents with asthma in relation with changes in maximal expiratory flow at 50 % of the forced vital capacity (MEF50), an index for the small airways.

Source: Journal of Allergy and Clinical Immunology - February 1, 2019 Category: Allergy & Immunology Authors: Taiga Kobori, Mizuho Nagao, Takao Fujisawa Source Type: research