Cellular and Humoral Responses to Lipopolysaccharide in Patients with Asymptomatic Bacteriuria and LatentPyelonephritis and Type 2 Diabetes Mellitus

Immune response to endotoxin (ET) or lipopolysaccharide (LPS) of gram-negative bacteria (GNB) may influence urinary tract infections (UTI), Asymptomatic bacteriuria (ABU) and latent Pyelonephritis (LP) in Type II diabetes mellitus (DM2) patients.
Source: Journal of Allergy and Clinical Immunology - Category: Allergy & Immunology Authors: Source Type: research

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ConclusionsFindings suggest that self-harm behavior and psychiatric disorders are associated with increased ED utilization for subsequent chronic disease-related ED utilization. Chronic disease among adolescent psychiatric patients should be attended to, potentially involving new models of clinical follow-up care.
Source: Journal of Adolescence - Category: Child Development Source Type: research
In this study, to estimate the states that are not directly available from the Bergman minimal model a high-order sliding mode observer is proposed. Then fractional calculus is combined with sliding mode control (SMC) for blood glucose regulation to create more robustness performance and make more degree of freedom and flexibility for the proposed method. Then an adaptive fractional-order SMC is proposed. The adaptive SMC protect controller against disturbance and uncertainties while the fractional calculus provides robust performance. Numerical simulation verifies that the proposed controllers have better performance in t...
Source: IET Systems Biology - Category: Biology Source Type: research
This paper deals with the design of robust observer based output feedback control law for the stabilisation of an uncertain nonlinear system and subsequently apply the developed method for the regulation of plasma glucose concentration in Type 1 diabetes (T1D) patients. The principal objective behind the proposed design is to deal with the issues of intra-patient parametric variation and non-availability of all state variables for measurement. The proposed control technique for the T1D patient model is based on the attractive ellipsoid method (AEM). The observer and controller conditions are obtained in terms of linear mat...
Source: IET Systems Biology - Category: Biology Source Type: research
We examined expression patterns of SGLTs in tumor tissues together with conventional pathological variables to determine prognostic significance in patients with renal cell carcinoma (RCC). Materials and Methods: Nephrectomy specimens were obtained from 68 patients. GLUT - 1, - 2 and SGLT - 1, - 2 expression in tumor and adjacent normal tissues were analyzed by immunohistochemical staining, and intensity was quantified using an image analyzer. Results: The four glucose transporters evaluated were broadly distributed in tumor tissues as well as throughout the normal parenchyma. There was no significant correlation between t...
Source: International Braz J Urol - Category: Urology & Nephrology Source Type: research
This study examined the association of adverse childhood experiences (ACEs) with early-onset chronic conditions.We analyzed data from the 2011–2012 Behavioral Risk Factor Surveillance System (BRFSS), which included 86,968 respondents representing a nine-state adult population of 32 million. ACE questions included physical, emotional, and sexual abuse; substance use, mental illness or incarceration of a household member; domestic violence, and parental separation. Outcomes included chronic conditions (cardiovascular disease, chronic obstructive pulmonary disease, cancer, depression, diabetes, and prediabetes); overall...
Source: Preventive Medicine - Category: International Medicine & Public Health Source Type: research
An 85-year-old woman with type 2 diabetes mellitus is admitted to the hospital due to a painful rash on her right leg. What's the next step in her care?Osmosis
Source: Medscape Med Students Headlines - Category: Universities & Medical Training Tags: Med Students Interactive Quiz Source Type: news
Conclusion: The overall 30-day readmission rate among patients following hospitalization for MS was 10.2%. The readmission rate was higher in older (>40 years) patients. The common causes of readmission were MS exacerbation, respiratory complications, and sepsis. A higher systemic disease burden, longer length of stay, and treatment with IVIG and PLEX were associated with higher risk of readmission. The readmissions were associated with higher cost of care and longer LOS compared to index admissions highlighting the economic impact of readmissions. Future strategies to lower the risk of readmissions in patients with MS ...
Source: Multiple Sclerosis and Related Disorders - Category: Neurology Source Type: research
Authors: Zhang K, Tang QL, Gao C PMID: 30892099 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - Category: Research Tags: Curr Med Res Opin Source Type: research
Source: BMJ Comments - Category: General Medicine Source Type: forums
The prediction or early diagnosis of maternal complications is challenging mostly because the main conditions, such as preeclampsia, preterm birth, fetal growth restriction, and gestational diabetes mellitus, are complex syndromes with multiple underlying mechanisms related to their occurrence. Limited advances in maternal and perinatal health in recent decades with respect to preventing these disorders have led to new approaches, and “ omics ” sciences have emerged as a potential field to be explored. Metabolomics is the study of a set of metabolites in a given sample and can represent the metabolic functionin...
Source: Clinics - Category: General Medicine Source Type: research
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