GSK-3 β regulates the endothelial-to-mesenchymal transition via reciprocal crosstalk between NSCLC cells and HUVECs in multicellular tumor spheroid models.

CONCLUSION: In summary, these findings suggest that targeting EndMT through GSK-3β inhibition in HUVECs might represent a promising therapeutic strategy for lung cancer therapy. PMID: 30709379 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/30709379?dopt=Abstract

Source: Clinical Lung Cancer - February 1, 2019 Category: Cancer & Oncology Authors: Kim SH, Song Y, Seo HR Tags: J Exp Clin Cancer Res Source Type: research