GSE124130 Expression data from adult mouse brain astrocytes

Contributors : Juan P Bolanos ; Carlos Vicente-GutierrezSeries Type : Expression profiling by arrayOrganism : Mus musculusWe aimed to investigate whether reduction of mitochondrial reactive oxygen species (mROS) in adult astrocytes altered the transcriptional profile in vivo. To do so, we used a genetic approach expressing a version of the catalase enzyme within the mitochondria of astrocytes. Astrocytes were acutely isolated from the brains of adult GFAP-mCAT and control mice by the immunomagnetic approach and subjected to a whole-genome transcriptomics array analysis.We used microarrays to detail the whole genome changes modulated by mROS levels in astrocytes.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by array Mus musculus Source Type: research