MiR-146a promotes oligodendrocyte progenitor cell differentiation and enhances remyelination in a model of experimental autoimmune encephalomyelitis.

This study provides insight into the cellular and molecular bases for the therapeutic effects of miR-146a on OPC differentiation and remyelination, and suggests the potential of enhancing miR-146a as a treatment of demyelinating disorders.
PMID: 30707940 [PubMed - as supplied by publisher]

Source: Neurobiology of Disease - January 29, 2019 Category: Neurology Authors: Zhang J, Zhang ZG, Lu M, Zhang Y, Shang X, Chopp M Tags: Neurobiol Dis Source Type: research