Elevated inflammatory parameter levels negatively correlate with populations of circulating stem cells (CD133+), early endothelial progenitor cells.

CONCLUSIONS: AIS patients exhibited increased numbers of early EPCs (CD133+/VEGFR2+) and AGF (VEGF and FGF) levels. A negative correlation between inflammatory parameters and AGFs and EPCs indicated the unfavourable influence of inflammatory factors on EPC differentiation and survival. Moreover, these correlations represented an important mechanism linking inflammation to vascular disease. PMID: 30706812 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30706812?dopt=Abstract

Source: Current Neurovascular Research - January 29, 2019 Category: Neurology Authors: Golab-Janowska M, Paczkowska E, Machalinski B, Kotlega D, Meller A, Nowacki P, Krzysztof S, Pawel W Tags: Curr Neurovasc Res Source Type: research