Mild Behavioral Impairment as a Marker of Cognitive Decline in Cognitively Normal Older Adults

Dementia, the most common cause of which is Alzheimer's disease (AD), affects an estimated 45 million people and is a leading cause of morbidity and death; it has devastating impact on people with the disease and those caring for them and costs the world economy around US $818 billion per year.1 Developing new and more effective treatments for AD is an urgent priority however there have been no new licensed pharmacologic therapies for 15 years.2 As such there is an increasing realization of the need for improved markers of early identification of people with pre-clinical AD, and their translation into effective stratification tools and a broader range of treatment targets.

Source: The American Journal of Geriatric Psychiatry - February 2, 2019 Category: Geriatrics Authors: Byron Creese, Helen Brooker, Zahinoor Ismail, Keith A Wesnes, Adam Hampshire, Zunera Khan, Maria Megalogeni, Anne Corbett, Dag Aarsland, Clive Ballard Tags: Regular Research Articles Source Type: research