Fractional laser technology reduces facial acne scarring

Fractional laser technology, often used in the removal of unwanted tattoos, can improve the appearance and texture of facial acne scars, based on data published online Nov.19 in JAMA Dermatology. “The evolution from traditional nanosecond to picosecond lasers has been observed to produce a...googletag.display('div-gpt-ad-cta');
Source: Skin and Allergy News - Category: Dermatology Tags: SAN Journals SAN Clinical News SAN News SAN Aesthetic Dermatology CME-candidate Source Type: news

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Peanut and soybean allergies are listed as contraindication in the package leaflet of isotretinoin, a widely used treatment of acne vulgaris. Cross-reactivity between PR10-proteins in peanut, tree nuts, and so...
Source: Allergy, Asthma and Clinical Immunology - Category: Allergy & Immunology Authors: Tags: Case Report Source Type: research
Background: The gold standard treatment for nodulocystic acne vulgaris, isotretinoin, is contraindicated in patients with a soy allergy as its capsule contains hydrogenated soybean oil. This has raised concern for its use in patients with peanut and cashew allergies due to the potential for cross-reactivity. Cashew allergy has been reported to confer a greater risk of cross-reactivity to soy, resulting in rare allergic reactions to isotretinoin. This case series sought to further evaluate the safety of isotretinoin use in eleven patients with a history of peanut or cashew allergy.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Authors: Source Type: research
Clin Cosmet Investig Dermatol. 2021 Jul 6;14:779-814. doi: 10.2147/CCID.S315711. eCollection 2021.ABSTRACTDermal filler treatments require constant reassessment for improving and safeguarding the rapidly evolving aesthetic field. Suboptimal injection technique, patient selection and product knowledge have touted a concerning increase in filler complications, with new challenges such as the COVID-19 pandemic leading to new paradigms in the understanding, prevention, diagnosis and treatment of complications. The updated 10-point plan has been developed to curtail complications through consideration of causative factors, cate...
Source: Clinical, Cosmetic and Investigational Dermatology - Category: Dermatology Authors: Source Type: research
CONCLUSION: Due to the various dimensions of skin organ involvement and the large population affected, long-term skin conditions following this pandemic can be a lot more problematic than it appears. Serious preventive measures and medical supports are necessary to avoid skin disorders from becoming permanent or even chronic.PMID:34097555 | DOI:10.1080/15569527.2021.1919138
Source: Cutaneous and Ocular Toxicology - Category: Toxicology Authors: Source Type: research
Discussion Corticosteroids are a group of drugs which can be naturally or synthetically produced. Naturally occurring substances are produced in the adrenal gland, and are protein-bound (primarily corticosteroid-binding globulin and albumin). In the target tissues, they may need to be converted to an active substance. They are then reduced, oxidized, hydroxylated or conjugated as measures to inactivate them. Synthetic steroids have less protein binding and depending on their structure are more or less resistant to inactivation. Prednisone is the glucocorticoid most often used for treatment, especially as it has a short hal...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
AAPS PharmSciTech. 2021 Apr 6;22(3):125. doi: 10.1208/s12249-021-01989-w.ABSTRACTThe main objective of the study was to prepare the microemulsions containing adapalene (MEs-Ap) to enhance epidermal penetration, dermal retention, and local bioavailability compared with the commercial preparation. The optimal formulations were selected by solubility experiments, pseudo-ternary phase diagram, and percutaneous permeation experiments and the physiochemical properties were also investigated. Then, the study of permeability, retention, safety, pharmacodynamics, and pharmacokinetics in the skin for MEs-Ap compared with the commerc...
Source: AAPS PharmSciTech - Category: Drugs & Pharmacology Authors: Source Type: research
Neutrophilic folliculitis is an inflammatory condition of hair follicles. In some neutrophilic folliculitis, such as in patients with acne and hidradenitis suppurativa, follicular hyperkeratosis is also observed. Neutrophilic folliculitis is often induced and/or exacerbated by a high-fat diet (HFD). However, the molecular mechanisms by which an HFD affects neutrophilic folliculitis are not fully understood.
Source: Journal of Allergy and Clinical Immunology - Category: Allergy & Immunology Authors: Source Type: research
Neutrophilic folliculitis is an inflammatory condition of hair follicles. In some neutrophilic folliculitis, such as acne and hidradenitis suppurativa, follicular hyperkeratosis is also observed. Neutrophilic folliculitis is often induced and/or exacerbated by high-fat diet (HFD). However, the molecular mechanisms by which HFD affects neutrophilic folliculitis are not fully understood.
Source: Journal of Allergy and Clinical Immunology - Category: Allergy & Immunology Authors: Source Type: research
Hidradenitis Suppurativa (HS), also known as acne inversa, is a chronic, painful, burdensome inflammatory disease manifesting in nodules and abscesses with progression to chronically draining tunnels in later-stage disease.
Source: Journal of Allergy and Clinical Immunology - Category: Allergy & Immunology Authors: Source Type: research
AbstractOral antibiotics are integral for treating inflammatory acne based on what is understood about the pathogenesis as well as the role ofCutibacterium acnes. However, rising concerns of antibiotic resistance and the perception of “antibiotic phobia” create potential limitations on their integration in an acne treatment regimen. When prescribing oral antibiotics, dermatologists need to consider dosage, duration, and frequency, and to avoid their use as monotherapy. These considerations are important, along with the use of newer strategies and compounds, to reduce adverse-event profiles, antibiotic resistanc...
Source: American Journal of Clinical Dermatology - Category: Dermatology Source Type: research
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