Two versus four puffs of albuterol: does dose change bronchodilator response?

Source: Journal of Asthma and Allergy - Category: Allergy & Immunology Tags: Journal of Asthma and Allergy Source Type: research

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ConclusionChildren with asthma with exacerbations compared to asthma children without exacerbations are characterized by increased airway obstruction since infancy through childhood. The airway obstruction is a fixed trajectory without progression due to exacerbations, suggesting that exacerbations are a consequence rather than a cause of diminished airway caliber in childhood.
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
Publication date: Available online 8 November 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): David Langton, Wei Wang, Joy Sha, Alvin Ing, David Fielding, Nicole Hersch, Virginia Plummer, Francis ThienAbstractBackgroundWhilst it is established that not all patients respond to bronchial thermoplasty (BT), the factors that predict response/non-response are largely unknown.ObjectivesThe aim of this study was to identify baseline factors that predict clinical response.MethodsThe records of 77 consecutive patients entered into the Australian Bronchial Thermoplasty Register were examined for bas...
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
AbstractPurpose of ReviewThis review summarizes the evidence leading towards the development of new guidelines that recommend early introduction of peanut to prevent the development of peanut allergy. It also reviews the current understanding of challenges faced with implementation of these recommendations on a widespread basis.Recent FindingsPrior recommendations to avoid feeding allergenic foods to infants have been updated and reversed. This paradigm shift in advice has created an opportunity on a population level to try and halt the recent increase in prevalence of peanut allergy. However, challenges with implementatio...
Source: Current Allergy and Asthma Reports - Category: Allergy & Immunology Source Type: research
Source: Journal of Allergy and Clinical Immunology - Category: Allergy & Immunology Authors: Source Type: research
We examined de-identified patient data from 28,508 unique encounters documented in the Asthma IQ database, obtaining patient level factors (demographics, asthma characteristics, co-morbidities), care setting (primary care physician [PCP] versus specialist physician [Allergist or Pulmonologist]), and guideline-defined levels of asthma control/severity. Rates of co-morbidities were identified by asthma severity and control and by care setting. We calculated odds ratios (ORs) for asthma control and severity based on each co-morbidity.ResultsBaseline demographic data indicated that patients seen by specialists versus PCPs, wer...
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
(American College of Allergy, Asthma, and Immunology) New study being presented at the American College of Allergy, Asthma and Immunology (ACAAI) Annual Scientific Meeting in Houston shows an association between a family history of cancer and a childhood asthma diagnosis.
Source: EurekAlert! - Cancer - Category: Cancer & Oncology Source Type: news
ConclusionThe lack of evidence-based gold standards for the diagnosis of SAD represents a challenge in clinical practice. In our cohort, we confirmed the insufficient correlation between different methods of specific PPV response measurement, and showed that theS. typhi Vi response was not contributive. Caution in the interpretation of results is warranted until more reliable diagnostic methods can be validated.
Source: Journal of Clinical Immunology - Category: Allergy & Immunology Source Type: research
Purpose of review Allergic rhinoconjunctivitis is the most common manifestation of allergic disease. This break in the normal natural function of the immune system to ignore harmless molecules such as pollen and pet dander to now aggressively react has lead to a substantial disease burden that is not always recognized and adequately treated. Recent findings Individual molecular component testing may increase the predictive value of blood sIgE and clinical symptoms. Defining the most symptoms inducing allergenic protein has led to advances in peptide-based allergen immunotherapy. There have been steady consistent repor...
Source: Current Opinion in Pediatrics - Category: Pediatrics Tags: ALLERGY, IMMUNOLOGY AND RELATED DISORDERS: Edited by Jordan S. Orange Source Type: research
Publication date: Available online 6 November 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Camille Bègne, Aurélien Justet, Clairelyne Dupin, Camille Taillé
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
AbstractPurpose of This ReviewTo highlight the evidence behind the various approved biologics indicated for asthma along with their specific targets in the inflammatory cascade and the role they serve in the management of allergic asthma.Recent FindingsThe mainstay of asthma management for the majority of asthmatics is inhaled corticosteroids with or without long-acting beta-agonists and/or leukotriene modifiers and/or tiotropium. However, in the small group of individuals with severe asthma uncontrolled with conventional therapy, biologics have emerged as an effective therapeutic option.SummaryAsthma is a chronic heteroge...
Source: Current Treatment Options in Allergy - Category: Allergy & Immunology Source Type: research
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