Propofol suppresses proliferation and migration of papillary thyroid cancer cells by down-regulation of lncRNA ANRIL.

CONCLUSION: Our findings suggested the in vitro anti-tumor potential of propofol in PTC. One possible mechanism involved in the anti-tumor activity was preliminary revealed: propofol down-regulated the expression of ANRIL, and thus blocking Wnt/β-catenin and NF-κB pathways.
PMID: 30703346 [PubMed - as supplied by publisher]

Source: Experimental and Molecular Pathology - January 28, 2019 Category: Pathology Authors: Chen F, Li M, Zhu X Tags: Exp Mol Pathol Source Type: research