Can acetaminophen/dimethyl sulfoxide formulation prevent accidental and intentional acetaminophen hepatotoxicity? - Algfeley SG, Al-Rejaie SS, Nagi MN.

An overdose of acetaminophen (APAP) causes liver injury in experimental animals and humans. The activation step (formation of reactive metabolite, N-acetyl-p-benzoquinone imine by cytochrome P450 system) and the consequent downstream pathway of oxidative s...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Poisoning Source Type: news