Anticatabolic Effects of Ketone Bodies in Skeletal Muscle

Publication date: Available online 31 January 2019Source: Trends in Endocrinology & MetabolismAuthor(s): Andrew P. Koutnik, Dominic P. D’Agostino, Brendan EganThe ketone bodies acetoacetate (AcAc) and β-hydroxybutyrate (βHB) are the subject of renewed interest given recently established pleiotropic effects regulating inflammation, oxidative stress, and gene expression. Anticatabolic effects of β-hydroxybutyrate have recently been demonstrated in human skeletal muscle under inflammatory insult, thereby expanding upon the wide-ranging therapeutic applications of nutritional ketosis.
Source: Trends in Endocrinology and Metabolism - Category: Endocrinology Source Type: research