Penile Histomorphometrical Evaluation in Hypertensive Rats Treated with Sildenafil or Enalapril Alone or in Combination: A Comparison with Normotensive and Untreated Hypertensive Rats

ConclusionsHypertension promoted structural alterations in the corpus cavernosum that may be related to ED. Enalapril‐ and sildenafil‐treated animals had preservation of normal corpus cavernosum structure and an increase in penile and cavernosal cross‐sectional area. The combination of these drugs showed less benefit than individual use. Felix‐Patrício B, Medeiros JL, Jr, De Souza DB, Costa WS, and Sampaio FJB. Penile histomorphometrical evaluation in hypertensive rats treated with sildenafil or enalapril alone or in combination: A comparison with normotensive and untreated hypertensive rats. J Sex Med **;**:**–**.
Source: The Journal of Sexual Medicine - Category: Sexual Medicine Authors: Tags: Original Research Source Type: research