Diagnosis and treatment of pediatric pulmonary arterial hypertension.

Diagnosis and treatment of pediatric pulmonary arterial hypertension.
Expert Rev Cardiovasc Ther. 2019 Jan 30;:
Authors: Farhat N, Lador F, Beghetti M
Abstract
INTRODUCTION: Paediatric pulmonary arterial hypertension (PAH) remains a rare and severe disease with a poor prognosis. PAH may be idiopathic, heritable or associated to systemic conditions in particular associated with congenital heart disease. Areas covered: A thorough and extensive diagnostic approach is required for a correct diagnosis. Outcome has improved over the last decade with a better diagnostic approach and with the initiation of new targeted therapies. However, there is still significant progress to achieve as there is still no cure for this devastating disease. Expert opinion: Adapted clinical studies to define the best therapeutic approach are needed. Even if the treatment approach is still mainly derived from adult data and expert consensus, several studies and registries are currently underway and should deliver important information in the next future. This review aims to give an overview about the current diagnosis and treatment strategies of PAH.
PMID: 30698043 [PubMed - as supplied by publisher]

Source: Expert Review of Cardiovascular Therapy - February 1, 2019 Category: Cardiology Tags: Expert Rev Cardiovasc Ther Source Type: research