Icariin protects vascular endothelial cells from oxidative stress through inhibiting endoplasmic reticulum stress

ConclusionThe results showed the dose-dependent effects of ICA against H2O2-induced injury in vascular endothelial cells. The inhibition of GRP78, ATF4 and eIF2α protein expressions in the ERS, and the subsequent alleviation of oxidative stress damage, might be the molecular mechanism.Please cite this article as: Wang FY, Jia J, Song HH, Jia CM, Chen CB, Ma J. Icariin protects vascular endothelial cells from oxidative stress through inhibiting endoplasmic reticulum stress. J Integr Med. 2019; Epub ahead of print.
Source: Journal of Integrative Medicine - Category: Complementary Medicine Source Type: research