The genetic and environmental relationship between childhood behavioral inhibition and preadolescent anxiety.
This study uses novel approaches to examine genetic and environmental influences shared between childhood behavioral inhibition (BI) and symptoms of preadolescent anxiety disorders. Three hundred and fifty-two twin pairs aged 9-13 and their mothers completed questionnaires about BI and anxiety symptoms. Biometrical twin modeling, including a direction-of-causation design, investigated genetic and environmental risk factors shared between BI and social, generalized, panic and separation anxiety. Social anxiety shared the greatest proportion of genetic (20%) and environmental (16%) variance with BI with tentative evidence for causality. Etiological factors underlying BI explained little of the risk associated with the other anxiety domains. Findings further clarify etiologic pathways between BI and anxiety disorder domains in children.
PMID: 30698127 [PubMed - as supplied by publisher]
Source: Twin Research and Human Genetics - Category: Genetics & Stem Cells Authors: Bourdon JL, Savage JE, Verhulst B, Carney DM, Brotman MA, Pine DS, Leibenluft E, Roberson-Nay R, Hettema JM Tags: Twin Res Hum Genet Source Type: research
More News: Anxiety | Children | Environmental Health | Generalized Anxiety Disorder (GAD) | Genetics | Separation Anxiety | Social Anxiety Disorder | Study