Amorphous nano-selenium quantum dots improve endothelial dysfunction in rats and prevent atherosclerosis in mice through Na+/H+ exchanger 1 inhibition.

CONCLUSION: A-SeQDs prevents endothelial dysfunction and the growth of atherosclerotic plaque through NHE1 inhibition and subsequent inactivation of Ca2+/calpain signaling. Clinically, the administration of A-SeQDs is an effective approach to treat atherosclerosis. PMID: 30695730 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30695730?dopt=Abstract

Source: Vascular Pharmacology - January 26, 2019 Category: Drugs & Pharmacology Authors: Zhu ML, Wang G, Wang H, Guo YM, Song P, Xu J, Li P, Wang SX, Yang L Tags: Vascul Pharmacol Source Type: research