Volume effects in radiosurgical spinal cord dose tolerance: how small is too small?

ConclusionsDmax has greater variability compared to D0.03  cc, D0.1 cc, and D1 cc, potentially creating risks when used for guidance for spinal cord. D0.03 cc may be an attractive alternative with higher reliability while its limits could be obtained by scaling the reported Dmax limit by a factor of 0.93. This may help guide treatment planning and aid in discovering true dose constraints for spine SBRT.
Source: Journal of Radiation Oncology - Category: Cancer & Oncology Source Type: research