Nonsuicidal self-injury and borderline personality features as risk factors for suicidal ideation among male veterans with posttraumatic stress disorder - Cunningham KC, Grossmann JL, Seay KB, Dennis PA, Clancy CP, Hertzberg MA, Berlin K, Ruffin RA, Dedert EA, Gratz KL, Calhoun PS, Beckham JC, Kimbrel NA.

U.S. veterans are at increased risk for suicide compared to their civilian counterparts and account for approximately 20% of all deaths by suicide. Posttraumatic stress disorder (PTSD) and borderline personality features (BPF) have each been associated wit...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news

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Chem. Commun., 2019, Accepted Manuscript DOI: 10.1039/C9CC06528H, CommunicationChenyao Hu, Zupeng Chen, Fengyan Han, Zixia Lin, Xiaofei Yang Ultrasmall and homogeneous bimetallic PdXBi nanoalloys are well distributed on Vulcan carbon support by a facile, low-cost synthetic strategy. The electrochemical activity of as-prepared homogeneous PdXBi nanoalloy/carbon black nanocomposites is... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Chem. Commun. latest articles - Category: Chemistry Authors: Source Type: research
Source: BMJ Comments - Category: General Medicine Source Type: forums
Source: BMJ Comments - Category: General Medicine Source Type: forums
ConclusionExtra-compartmental extension of tumor and a higher-grade lesion is significantly associated with development of recurrence in cases of GCT of bone.
Source: Annals of Medicine and Surgery - Category: General Medicine Source Type: research
A new study examining the role that star-shaped brain cells called astrocytes play in Huntington ’s disease has identified a potential strategy that may halt the disease and repair some of the damage it causes.Astrocytes interact with and support neurons, or nerve cells, and other brain cells. Although astrocytes outnumber neurons, little is known about how they interact with synapses, the junctions between neurons that enable them to communicate and convey messages to each other.The study, led by UCLA researchers and published in the journal Science Translational Medicine, found that Huntington ’s disease dama...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
Publication date: Available online 15 October 2019Source: Pharmacology &TherapeuticsAuthor(s): Edward D. Chan, Michael M. Chan, Mallory M. Chan, Paul E. MarikAbstractGlucocorticoids (GC) in all its various forms and formulations are likely one of the most commonly used pharmacologic agents in medicine. Their use can be profoundly therapeutic but are also associated with a myriad of acute and chronic side effects. It is fairly well-accepted in the medical community that GC can be life-saving when used in critically ill patients with severe exacerbations of asthma and chronic obstructive pulmonary disease, HIV-associated...
Source: Pharmacology and Therapeutics - Category: Drugs & Pharmacology Source Type: research
AbstractCortical spreading depression (CSD) is a wave of transient intense neuronal firing leading to a long lasting depolarizing block of neuronal activity. It is a proposed pathological mechanism of migraine with aura. Some forms of migraine are associated with a genetic mutation of the Nav1.1 channel, resulting in its gain of function and implying hyperexcitability of interneurons. This leads to the counterintuitive hypothesis that intense firing of interneurons can cause CSD ignition. To test this hypothesis in silico, we developed a computational model of an E-I pair (a pyramidal cell and an interneuron), in which the...
Source: Journal of Computational Neuroscience - Category: Neuroscience Source Type: research
Conclusion It is clear that clinically, there is still much to be learnt about alexithymia and its relationship with a range of related phenomena. Firstly, is alexithymia a continuous and stable trait independent of psychological or somatic symptomology that is developed during childhood? Or is it instead a reactive state induced by trauma and distress at any age, which serves to defend against intense and upsetting emotions? This impacts on treatment options. For example, should we be focussing on early childhood interventions which target the child's emotional environment and parenting to encourage emotional exp...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
Conclusion We must take steps to recognize psychological trauma among our partners and ourselves, establish a supportive culture of understanding and help seeking, and realize that we are ineffective in caring for others if we do not first help ourselves. Highly effective treatments are available. References Boffa JW, Stanley IH1, Hom MA. PTSD symptoms and suicidal thoughts and behaviors among firefighters. J Psychiatr Res. 2017;84:277­–283. Substance Abuse and Mental Health Services Administration. (Sept. 4, 2014.) Substance use and mental health estimates from the 2013 National Survey on Drug Use and He...
Source: JEMS Special Topics - Category: Emergency Medicine Authors: Tags: Exclusive Articles Resiliency Operations Source Type: news
ConclusionsSimilar to treatment studies of nonbipolar MDD, the treatment studies of bipolar depression frequently excluded patients with comorbid psychiatric and substance use disorders and insufficient severity of depressive symptoms as rated on standardized scales. These findings indicate that concerns about the generalizability of data from trials of recently approved medications for the treatment of bipolar depression are as relevant as the concerns that have been raised about studies of antidepressants for nonbipolar depression.
Source: CNS Drugs - Category: Neurology Source Type: research
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