Clinical Analysis of the Patients With Cavitary Pulmonary TB and Endobronchial TB in the PPM-UUH Cohort

Conditions:   Tuberculosis;   Tuberculosis, Pulmonary;   Cavity;   Cavitary Pulmonary Tuberculosis;   Endobronchial Tuberculosis;   Bronchoscopy;   Acid Fast Bacilli Infection;   Drug Susceptible Test (DST);   Multi-drug Resistant Tuberculosis;   Ant-tuberculous Agent;   Transmission;   Insolation Intervention:   Other: Observation of AFB smear/culture Sponsors:   University of Ulsan;   Ulsan University Hospital Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials

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Introduction: The diagnosis of pulmonary tuberculosis(PT) is based on clinical and radiological arguments but a microbiologic or histologic proof is a gold standard. Bronchoscopic procedures, biopsy techniques and conventional surgery could play a primary role in PT diagnosis, particularly in patients with scarce sputum or negative sputum smearAim: Emphasize contribution of invasive techniques in the diagnosis of PTMethods: Retrospective study(2011-2018)including patients with PT and treated according to WHO recommendations in pulmonary department C(Mami hospital in Tunisia). Population was divided into two groups:G1(n=112...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Tuberculosis Source Type: research
Conditions:   Tuberculosis;   Tuberculosis, Pulmonary;   Cavity;   Cavitary Pulmonary Tuberculosis;   Endobronchial Tuberculosis;   Bronchoscopy;   Acid Fast Bacilli Infection;   Drug Susceptible Test (DST);   Multi-drug Resistant Tuberculosis;   Ant-tuberculous Agent;   Transmission;   Insolation Intervention:   Other: Observation of AFB smear/culture Sponsors:   University of Ulsan;   Ulsan University Hospital Completed
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
In this article, we present a unique case of active pulmonary tuberculosis, with multiple huge “cluster” signs like fireworks, together with multiple “galaxy” signs. The repeated acid‐fast sputum smears and both bronchial washings were all negative forMycobacterium tuberculosis, but the acid ‐fast culture of sputum taken soon after the first bronchoscopy, and pleural fluid, turned out to be positive forM. tuberculosis at six weeks after admission. The present case clearly demonstrates that the “galaxy” and “cluster” signs are red herring signs of the low rates of isolatin...
Source: Respirology Case Reports - Category: Respiratory Medicine Authors: Tags: Case Report Source Type: research
Abstract OBJECTIVE: To evaluate utility of Xpert MTB/RIF in bronchoalveolar lavage fluid in children with probable pulmonary tuberculosis. METHODS: Children with probable pulmonary tuberculosis with negative smear and Xpert on induced sputum/gastric aspirate were subjected to bronchoalveolar lavage (BAL) for Xpert assay and mycobacterial liquid culture. Data of children
Source: Indian Pediatrics - Category: Pediatrics Authors: Tags: Indian Pediatr Source Type: research
Conclusion: Use of r-EBUS allows to receive biopsy directly from the target PPLs in patients with smear negative TB that is important for early treatment and avoiding of false therapy
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Tuberculosis Source Type: research
Conclusion: introduction of flexible bronchoscopy in tertiary care centres greatly increase the detection of not only new cases of tuberculosis at an early stage, but also Multi-drug resistance Tuberculosi.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Tuberculosis Source Type: research
Conclusion: Bronchial washing Gene Xpert has an excellent diagnostic yield for detection of mycobacterium tuberculosis in smear negative cases of suspected pulmonary tuberculosis.
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Tuberculosis Source Type: research
This study was undertaken to compare the yield of sputum, induction with bronchoalveolar lavage (BAL) in smear-negative suspected pulmonary TB patients in a tertiary care hospital in Agra. METHODS: Fifty patients were included in the study. In all patients, induced sputum, fibreoptic bronchoscopy and BAL fluid were subjected to diagnostic testing. RESULTS: On acid-fast smear examination, induced sputum and BAL fluid tested positive in 27/50 and 25/50 patients, respectively with a sensitivity of 83.3% and 90% respectively (p
Source: Indian Journal of Chest Diseases and Allied Sciences - Category: Respiratory Medicine Tags: Indian J Chest Dis Allied Sci Source Type: research
Publication date: 2018Source: Respiratory Medicine Case Reports, Volume 24Author(s): Mohammed Abdalla, Pavel Sinyagovskiy, Wiam Mohamed, Amro AbdelghaniAbstractA 58 years old male who was admitted to the intensive care unit for septic shock secondary to pneumonia, he has Crohn's disease currently treated with Vedolizumab and previously with infliximab. He was started on broad spectrum antibiotics and vasopressors for treatment of septic shock without improvement in the following days, sputum &blood cultures were negative. Bronchoscopy was done for non-resolving pneumonia work up, broncheoalveolar lavage smears and cult...
Source: Respiratory Medicine Case Reports - Category: Respiratory Medicine Source Type: research
Abstract A 58 years old male who was admitted to the intensive care unit for septic shock secondary to pneumonia, he has Crohn's disease currently treated with Vedolizumab and previously with infliximab. He was started on broad spectrum antibiotics and vasopressors for treatment of septic shock without improvement in the following days, sputum &blood cultures were negative. Bronchoscopy was done for non-resolving pneumonia work up, broncheoalveolar lavage smears and cultures were negative for bacteria, tuberculosis and Fungi. Bronchial washings cytology showed filariform larvae and serology was positive for St...
Source: Respiratory Care - Category: Respiratory Medicine Authors: Tags: Respir Med Case Rep Source Type: research
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