Infective Endocarditis Related to Injection Drug Use Rising
WEDNESDAY, Jan. 30, 2019 -- The risk for infective endocarditis related to injection drug use increased from 2006 to 2015, according to a study published online Jan. 28 in CMAJ, the journal of the Canadian Medical Association. Matthew A. Weir, M.D.,...
We described our modification of reconstruction of the aortic root, the left ventricular outflow tract and the intervalvular fibrous body with neighbouring structures after radical resection following extensive infective endocarditis. This technique may be useful for those patients who otherwise would be non-operable.
MitraClip Therapy for Healed Infective Endocarditis - How Long Should We Wait After Active Infection? Circ J. 2019 Oct 10;: Authors: Kato Y, Amaki M, Kanzaki H, Kataoka Y, Okada A, Miyamoto K, Hamatani Y, Amano M, Takahama H, Hasegawa T, Matsumoto Y, Fujita T, Kobayashi J, Ishibashi-Ueda H, Yasuda S, Izumi C PMID: 31597888 [PubMed - as supplied by publisher]
A new blood filtration technology may prove to be life-saving for patients whose normally healthy inflammatory response to injury or illness has gone into overdrive, resulting in fatally high levels of cytokines in their blood. In an interview with MD+DI, Dr. Phillip Chan, MD, PhD, CEO of CytoSorbents Corp., explained that inflammation, and the production of substances called cytokines that drive inflammation, are the bodyâs natural response to heal injury or infection. But sometimes, the inflammatory response is so severe in such conditions as sepsis and infection, burn injuries, trauma, pancreatitis, li...
Genome studies of heart valve tissue (HVT) in patients with structural valvular heart disease (sVHD) and acute infective endocarditis (aIE) showed polymicrobial infections. Subject of this study is the quantification of bacterial DNA in HVT of sVHD in comparison to aIE. It will be examined whether the bacterial DNA concentration can be used as surrogate marker to differentiate chronic and acute infections. DNA was isolated from HVT of 100 patients with sVHD and 23 microbiologically positively tested patients with aIE.
This editorial refers to ‘Clinical presentation, aetiology, and outcome of infectious endocarditis. Results of the ESC-EORP EURO-ENDO (European infectious endocarditis) registry: a prospective cohort study’††, by G. Habibet al., on page3222.
Conclusion: Diagnostic splenectomy has high diagnostic utility in the evaluation of PUO patients with reticuloendothelial system involvement after an extensive negative investigative workup. The diagnosis of lymphoma in such patients is more common than an infective cause. PMID: 31562716 [PubMed - in process]
Authors: Lafaurie GI, Noriega LA, Torres CC, Castillo Y, Moscoso SB, Mosquera S, Díaz-Báez D, Chambrone L Abstract BACKGROUND: Antibiotic prophylaxis (AP) is used routinely in high-risk groups of patients to reduce bacteremia and the risk of developing infective endocarditis (IE). In this systematic review, the authors evaluated the efficacy of AP on the incidence, nature, magnitude, and duration of post-dental procedure bacteremia. METHODS: The authors conducted a systematic search of the literature using MEDLINE, Embase, and the Cochrane Central Register of Controlled Trials up to and including ...
Infective endocarditis (IE) is a devastating disease with high mortality. Most guidelines recommend routine use of antibiotic prophylaxis during oral surgery to prevent IE in patients with specific predisposing cardiac conditions, but this is not the case in the UK. The conflicting opinions and guidance are confusing and may affect IE prophylaxis implementation. We investigated how IE prophylaxis standards are defined in hospitals and outpatient clinics of oral and maxillofacial surgery. A survey was sent to 80 surgeons heading departments of oral and maxillofacial surgery in Germany.
We report the case of a 65-year-old woman who developed candidemia and endocarditis by C. glabrata with a newly acquired FKS mutation 24 months after successful treatment of infective endocarditis by C. glabrata with a double dosage of anidulafungin (200 mg daily) followed by oral voriconazole. Driven by high echinocandin MICs the strain taken by intraoperative cultures was further analyzed in a referral microbiology laboratory, confirming the new onset of point mutation S633P of the FKS2 gene. PMID: 31545778 [PubMed - in process]