Acute kidney injury: TRPM2 and RAC1: mediators of oxidative stress in AKI

Nature Reviews Nephrology 10, 674 (2014). doi:10.1038/nrneph.2014.206 Kidney ischaemia is associated with a loss of intracellular potassium and an increase in intracellular levels of sodium, chloride and calcium; however, the mechanisms involved in the loss of cellular ion homeostasis are unknown. A new study has revealed a critical role for the nonselective
Source: Nature Reviews Nephrology - Category: Urology & Nephrology Tags: Research Highlight Source Type: research