MicroRNA regulating stanniocalcin-1 is a metastasis and dissemination promoting factor in glioblastoma

ConclusionsSTC1 may be a novel metastasis/metastatic dissemination promoting factor regulated by several miRs in GBM. Because STC1 is a secreted glycoprotein and functions via the autocrine/paracrine signals, inhibiting STC1 signal may become a novel therapeutic strategy for GBM.

Source: Journal of Neuro-Oncology - January 30, 2019 Category: Cancer & Oncology Source Type: research