Pain mechanism of oral ulcerative mucositis and the therapeutic traditional herbal medicine hangeshashinto

ConclusionElucidation of the pain mechanism of oral ulcerative mucositis and analgesic mechanism of hangeshashinto will allow identification of novel therapeutic approaches against oral ulcerative mucositis-induced pain in patients. The traditional Japanese herbal medicine hangeshashinto is a reliable drug with supporting scientific evidence.
Source: Journal of Oral Biosciences - Category: Biomedical Science Source Type: research

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We report a case of deep vein thrombosis in the upper limb after trauma to the shoulder causing grade III Rockwood acromioclavicular dislocation.ResumenUn 5-10% de las trombosis venosas profundas ocurren en el miembro superior. Su causa más frecuente suele ser secundaria a cáncer, catéter venoso central, tratamiento con radio-quimioterapia u hormonal. Con menor frecuencia, los traumatismos en la región del hombro también pueden ser causantes de una trombosis venosa profunda. Su diagnóstico probablemente sea más complejo que en la extremidad inferior debido a su baja frecuenc...
Source: Revista Espanola de Cirugia Ortopedica y Traumatologia - Category: Orthopaedics Source Type: research
ConclusionPrimary adenocarcinoma of the jaw is extremely rare, except for 2–3% central mucoepidermoid carcinomas. The possibility of a metastatic tumor should be a consideration when encountering unusual histomorphology of an adenocarcinoma in the jaw bone.
Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology - Category: ENT & OMF Source Type: research
Conditions:   Oral Mucositis (Ulcerative);   Oral Mucositis (Ulcerative) Due to Radiation;   Oral Mucositis (Ulcerative) Due to Antineoplastic Therapy;   Head and Neck Cancer Interventions:   Device: Photobiomodulation;   Other: Routine Oral Care and Analgesia Sponsors:   MuReva Phototherapy Inc.;   Ohio State University Comprehensive Cancer Center;   Hackensack Meridian Health Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
The aim of this paper was to evaluate the activity and tolerability of oral vinorelbine in patients with advanced castration resistant prostate cancer (CRPC) who progressed after a minimum of three lines including: abiraterone acetate, docetaxel, cabazitaxel, and enzalutamide. Treatment consisted of weekly oral vinorelbine 60 mg/m2. Chemotherapy was administered until disease progression or unacceptable toxicity. Twenty-six patients received vinorelbine: their median age was 74 years (range 58–84 years). Twenty-four (92.3%) patients had bone metastases. A decrease in PSA levels ≥50% was observed in 2 patients ...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research
Rationale: Gastric cancer is still one of the most common cancer in East Asia. More than 70% gastric cancer patients are diagnosed at an advanced stage in China. Moreover, about 10% cases are unresectable which usually suffer a poor prognosis with a median survival time of 5 to 12 months. In recent years, some clinical studies found that many unresectable gastric cancer cases could get opportunity for surgery after treatment that improve prognosis significantly Patient concerns: 64-year-old male patient was admitted with upper abdominal pain. Upper gastrointestinal endoscopy showed a large ulcerated tumor located from...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
​BY JENNIFER TUONG; IVAN KHARCHENKO; JEAN LUC AGARD; &AHMED RAZIUDDIN, MDA 65-year-old man who had HIV well-controlled with highly active antiretroviral therapy, hypertension, sciatica, and restless leg syndrome presented to the emergency department with left leg pain. He also had had chemotherapy and radiation for anal cancer. The patient said the pain had started 45 minutes earlier when he was sitting on the toilet.He described the pain as sore in quality and 10/10 on the pain scale. He reported that it had started in his lower back and radiated to his left leg. He said he had had no trauma or weakness to the regio...
Source: The Case Files - Category: Emergency Medicine Tags: Blog Posts Source Type: research
Colorectal cancer is one of the main neoplasms worldwide; at the time of diagnosis about 25% of cases already have an advanced stage with the presence of metastases. A 58-year-old female presented with nausea, vomiting, and black stools and diffuse abdominal pain associated with 7% weight loss. She was referred to our hospital with signs of digestive tract bleeding and anemic syndrome. Panendoscopy revealed body and fundus gastropathy and presence ofHelicobacter pylori, and colonoscopy showed a neoplastic lesion at the ascending colon level. A synchronous resection was performed in a single surgical time of colorectal canc...
Source: Case Reports in Gastroenterology - Category: Gastroenterology Source Type: research
Authors: Makary P, Parmar JR, Mims N, Khanfar NM, Freeman RA Abstract The use of cannabis medications has grown in recent years for the symptomatic relief of chemotherapy-induced nausea/vomiting (CINV) and chronic pain (cancer-related and non-cancer-related). As states legalize the use of cannabis, it is important for pharmacists and other health care professionals to be aware of how to counsel patients receiving prescriptions for cannabis medications. The aim of this study was to develop patient counseling guidelines for the use of cannabis products in treatment of CINV and chronic pain. A literature search was pe...
Source: Journal of Pain and Palliative Care Pharmacotherapy - Category: Palliative Care Tags: J Pain Palliat Care Pharmacother Source Type: research
This study aims to investigate the influence of BAHS and associated skin reactions around the implant. A total of 45 patients were prospectively followed from implantation up to at least 1 year. Swabs were obtained at baseline, 12 weeks follow-up and during cases of inflammation (Holgers score ≥2). The microbiota was assessed using IS-proTM, a bacterial profiling method based on the interspace region between the 16S–23S rRNA genes. Detection of operational taxonomic units, the Shannon Diversity Index, sample similarity analyses and Partial Least Squares Discriminant Analysis (PLS-DA) were employed. Staphylococcus ...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
Conclusions: Pediatric patients with head and neck cancer can be risk-stratified based on clinical and dosimetric factors. This data, combined with parent and patient perceptions, is key to the development of rational guidelines.
Source: Journal of Pediatric Hematology Oncology - Category: Hematology Tags: Online Articles: Original Articles Source Type: research
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