Effects of controlled ovarian stimulation on thyroid stimulating hormone in infertile women

Publication date: Available online 30 January 2019Source: European Journal of Obstetrics &Gynecology and Reproductive BiologyAuthor(s): Yuan-Jie Du, Xin Xin, Na Cui, Lei Jiang, Ai-Min Yang, Gui-Min Hao, Bu-Lang GaoAbstractObjectiveTo study the effects of long-acting gonadotropin-releasing hormone agonist (GnRH-a) on thyroid function in euthyroid patients of in vitro fertilization (IVF)/ intracytoplasmic sperm injection of embryo transfer (ICSI-ET) and to investigate the timing and alteration of thyroid stimulating hormone (TSH) during controlled ovarian stimulation(COS)Materials and methodsEuthyroid patients scheduled for IVF/ICSI were enrolled. Euthyroidism was defined as having no history of hypothyroidism with normal TSH before IVF. Long GnRH-a protocol was chosen as COS protocol. 207 patients were divided into two groups based on basal serum TSH level: group A with 0.35mIU/L<TSH<2.5mIU/L (n = 137) and group B with 2.5mIU/L ≤ TSH<4.5mIU/L (n = 70). Serum TSH was tested on 6 time points: before COS (2-5days in menstrual cycle, before GnRH-a injection), Gn injection day 1, Gn injection day 5, human chorionic gonadotropin (HCG) day, 14 and 28 days after transplantation. The serum TSH, clinical pregnancy and abortion rate were investigated.ResultThe serum TSH value was significantly (P 
Source: European Journal of Obstetrics and Gynecology and Reproductive Biology - Category: OBGYN Source Type: research

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Publication date: Available online 19 October 2019Source: Mutation Research/Genetic Toxicology and Environmental MutagenesisAuthor(s): Ketsia Sabrina do Nascimento Marinho, Clovis José Cavalcanti Lapa Neto, Ilka Dayane Duarte de Sousa Coelho, Meykson Alexandre da Silva, Maria Eduarda Gomes Melo, Katharine Raquel Pereira dos Santos, Cristiano Aparecido Chagas, Álvaro Aguiar Coelho Teixeira, Valéria Wanderley TeixeiraAbstractExposure of pregnant women to pesticides in an occupational or incidental manner has been pointed out as a possible cause of health problems in newborns. Cypermethrin and methomyl ar...
Source: Mutation Research Genetic Toxicology and Environmental Mutagenesis - Category: Genetics & Stem Cells Source Type: research
Abstract Follicular unit excision (FUE) requires the careful excision of hair-bearing follicular units. The follicle can only be detached from the skin once the epidermis, dermis, and subcutaneous tissues are cut, and each layer requires a different amount of force. Traditional FUE devices can be set only to a single speed during a single excision. The Trivellini Device is a first-in-class programmable multiphasic device that is able to accommodate the cutting of various layers of tissue in a single program, while ensuring minimal transection of hair grafts. We detail the advances in the field of motorized FUE emb...
Source: Skinmed - Category: Dermatology Authors: Tags: Skinmed Source Type: research
In this study, AT1-AAs were detected in the sera of patients with peripheral arterial disease (PAD) and the positive rate was 44.44% vs. 17.46% in non-PAD volunteers. In addition, analysis showed that AT1-AAs level was positively correlated with PAD. To reveal the causal relationship between AT1-AAs and vascular aging, an AT1-AAs-positive rat model was established by active immunization. The carotid pulse wave velocity was higher, and the aortic endothelium-dependent vasodilatation was attenuated significantly in the immunized rats. Morphological staining showed thickening of the aortic wall. Histological examination showe...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
The main aim of physical activity in pregnancy is to achieve health-enhancing benefits in a way that is safe, enjoyable and sustainable.
Source: Washington Post: To Your Health - Category: Consumer Health News Authors: Source Type: news
Publication date: Available online 19 October 2019Source: Biochimica et Biophysica Acta (BBA) - Reviews on CancerAuthor(s): Subash C. Gupta, Nikee Awasthee, Vipin Rai, Srinivas Chava, Venugopal Gunda, Kishore B. ChallagundlaAbstractThe regulation of the pleiotropic transcription factor, nuclear factor-κB (NF-κB) by miRNAs and proteins is extensively studied. More recently, the NF-κB signaling was also reported to be regulated by several long non-coding RNAs (lncRNAs) that constitute the major portion of the noncoding component of the human genome. The common NF-κB associated lncRNAs include NKILA, H...
Source: Biochimica et Biophysica Acta (BBA) Reviews on Cancer - Category: Cancer & Oncology Source Type: research
Silvina Beatriz Meroni, María Noel Galardo, Gustavo Rindone, Agostina Gorga, María Fernanda Riera and Selva Beatriz Cigorraga* Centro de Investigaciones Endocrinológicas “Dr César Bergadá” CONICET-FEI-División de Endocrinología Hospital de Niños Ricardo Gutiérrez, Buenos Aires, Argentina Sertoli cells are somatic cells present in seminiferous tubules which have essential roles in regulating spermatogenesis. Considering that each Sertoli cell is able to support a limited number of germ cells, the final number of Sertoli cells reached during...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
Jie Cai1†, Yi Zhang1†, Yuying Wang1, Shengxian Li1, Lihua Wang1, Jun Zheng1, Yihong Jiang1, Ying Dong1, Huan Zhou1, Yaomin Hu1, Jing Ma1, Wei Liu1,2*† and Tao Tao1*† 1Division of Endocrinology and Metabolism, Department of Internal Medicine, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Pudong, China 2Shanghai Key Laboratory for Assisted Reproduction and Reproductive Genetics, Center for Reproductive Medicine, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Pudong, China Background: Infertility and dyslipidemia are frequently present in both women...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
Publication date: July 2018Source: The Lancet Diabetes &Endocrinology, Volume 6, Issue 7Author(s): Simone De Leo, Elizabeth N PearceSummaryUnderstanding of changes in thyroid function and the consequences of thyroid disease during pregnancy has rapidly grown in the past two decades, and revised American Thyroid Association guidelines on this topic were published in 2017. This Review explores the association between thyroid autoimmunity and complications during and after pregnancy. Thyroid autoimmunity refers to the presence of antibodies to thyroperoxidase or thyroglobulin, or thyroid-stimulating hormone receptor antib...
Source: The Lancet Diabetes and Endocrinology - Category: Endocrinology Source Type: research
Fertility specialists have long noticed a relationship between thyroid disorders and reproductive health issues including irregular periods, difficulty getting pregnant, and multiple miscarriages early in pregnancy. During Thyroid Awareness Month and with new research, it's worth knowing about a not uncommon and treatable problem that may be affecting your plans for a new family. An underactive thyroid (hypothyroidism) or overactive thyroid (hyperthyroidism) may be present even in healthy young women and can affect reproduction at every stage from conception, poor fetal growth, premature birth and stillbirth. Not having en...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
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