Nrf2 deficiency exacerbates frailty and sarcopenia by impairing skeletal muscle mitochondrial biogenesis and dynamics in an age-dependent manner.

CONCLUSION: Nrf2 deficiency exacerbated frailty and sarcopenia during aging, at least partially by impairing skeletal muscle mitochondrial biogenesis and dynamics in an age-dependent manner. PMID: 30690066 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30690066?dopt=Abstract

Source: Experimental Gerontology - January 25, 2019 Category: Geriatrics Authors: Huang DD, Fan SD, Chen XY, Yan XL, Zhang XZ, Ma BW, Yu DY, Xiao WY, Zhuang CL, Yu Z Tags: Exp Gerontol Source Type: research