Chronic Kidney Disease and the Adiposity Paradox: Valid or Confounded?

Obesity, defined by body mass index (BMI), is associated with lower mortality risk in patients with chronic kidney disease (CKD). BMI and % body fat (%BF) are confounded by muscle mass, while DXA derived fat mass index (FMI) overcomes this limitation. We compared the associations between obesity and mortality in persons with CKD using multiple estimates of adiposity, and determined whether muscle mass, inflammation and weight loss modify these associations.

https://www.jrnjournal.org/article/S1051-2276(18)30283-8/fulltext?rss=yes

Source: Journal of Renal Nutrition - January 29, 2019 Category: Urology & Nephrology Authors: Susan L. Ziolkowski, Jin Long, Joshua F. Baker, Glenn M. Chertow, Mary B. Leonard Tags: Original Research Source Type: research