Treatment outcomes according to the macroscopic tumor type in locally advanced esophageal squamous cell carcinoma treated by chemoradiotherapy
ConclusionsMacroscopic tumor type 1 was the significant favorable predictive factor for local control. The study results suggested that the macroscopic tumor type was useful in predicting tumor responses.
ConclusionAngiogenesis at the early stage of ESCC progression is configured by the balance between accelerator (angiogenic factors from both cancer cells and SMCs) and brake (angiogenic inhibitor) factors.
Abstract Esophageal squamous cell carcinoma (ESCC) and esophagogastric junction adenocarcinoma (EGJA) are the two main types of gastrointestinal cancers that pose a huge threat to human health. ESCC remains one of the most common malignant diseases around the world. In contrast to the decreasing prevalence of ESCC, the incidence of EGJA is rising rapidly. Early detection represents one of the most promising ways to improve the prognosis and reduce the mortality of these cancers. Current approaches for early diagnosis mainly depend on invasive and costly endoscopy. Non-invasive biomarkers are in great need to facil...
Authors: Tsunoda M, Miura Y, Osawa H, Khurelbaatar T, Sakaguchi M, Fukuda H, Lefor AK, Yamamoto H Abstract A 62-year-old man with a flat early esophageal cancer was referred for endoscopic treatment. White light imaging revealed a pale red lesion, whereas linked color imaging (LCI) and blue laser imaging (BLI) yielded purple and brown images, respectively. Iodine staining demonstrated a large unstained area with a homogenous but very weak pink-color sign. This area appeared more clearly as purple and green on LCI and BLI, respectively; however, a different colored portion was observed at the 4 o'clock position insi...
We developed a computer-assisted diagnostic (CAD) system for real-time automated diagnosis of precancerous lesions and early esophageal squamous cell carcinoma (ESCC) to assist the diagnosis of esophageal cancer.
We developed a system for computer-assisted diagnosis (CAD) for real-time automated diagnosis of precancerous lesions and early esophageal squamous cell carcinomas (ESCCs) to assist the diagnosis of esophageal cancer.
Conclusion: In Feicheng population, tobacco smoking or alcohol consumption may not be risk factors of EPLs. Low-quality drinking water raised the EPLs risk. Bad house heating materials, such as cereal straw, may lead to high EPLs risk.
Endoscopic submucosal dissection (ESD) is a useful and curative treatment for noninvasive superficial esophageal squamous cell carcinoma (SESCC). However, metachronous esophageal cancer (MEC) is commonly observed in the background mucosa after ESD. Varying risk factors of MEC have been reported by different studies.
Esophageal cancer is common cancer and common cause of cancer-related death. Although the incidence of esophageal adenocarcinoma is increasing rapidly in Europe and North America, squamous cell carcinoma (SCC) remains the most common tumor type. Cancer invasion depth is a critical factor affecting the choice of treatment in patients with superficial SCC. However, the diagnosis of invasion depth is currently subjective and liable to inter-observer variability. A potential solution to mitigate the variability and complexity associated with diagnosing cancer invasion depth involves the application of computerized image analys...
Esophageal cancer is the eighth most common cancer worldwide, and the sixth cause of death. When esophageal cancer is diagnosed in advanced stage, it will require highly invasive treatments and its prognosis will be poor, thus it is important to detect in early stage. We have reported the great ability of artificial intelligence (AI) to detect esophageal cancer including squamous cell carcinoma (SCC) and adenocarcinoma in still pictures. Here, we demonstrated the diagnostic ability of AI to detect superficial esophageal SCC in movies.
Endoscopic resection is increasingly being recommended for both squamous and adenocarcinoma early-stage esophageal cancers. Most analyses for early-stage cancers in the U.S. as well as the corresponding guidelines have been derived from data from the adenocarcinoma histology. Given that the tumor biology may differ considerably, we compared early-stage esophageal squamous cell carcinoma (ESCC) to early-stage adenocarcinoma (EAC) in a large, representative, U.S. population database containing data on both tumor subtypes.