Closing the Divide in Access to Palliative Care and Pain Relief

NCI ’ s Center for Cancer Research (CCR) Grand Rounds Dr. Felicia Marie Knaul received a master ’ s and doctoral degree in Economics from Harvard University. She undertakes global health research, advocacy and policymaking focused on reducing inequities and improving the socio-economic conditions of vulnerable populations, with emphasis on Latin America. Her main areas of research include access to palliative care and pain relief, global cancer care and control, women and health, health system reform and finance, gender-based violence and children in especially difficult circumstances. At the University of Miami, she is the Director of the Institute for Advanced Study of the Americas, Professor at the Miller School of Medicine and a member of the Sylvester Comprehensive Cancer Center. Prior to that, Dr. Knaul was associate professor at the Harvard Medical School and Director of the Harvard Global Equity Initiative, a program chaired by Nobel Laureate Amartya Sen. Dr. Knaul maintains a synergistic program of health research and global advocacy grounded in Mexico. She leads a research team at the Mexican Health Foundation, is a member of the Mexican National Academy of Medicine and is a senior member of the Mexican National System of Researchers. She is also the Founding President of T ó matelo a Pecho, an NGO dedicated to producing evidence to reduce the global burden of cancer and the immediate past President of the Latin American Union Against Women &rsquo...
Source: Videocast - All Events - Category: General Medicine Tags: Upcoming Events Source Type: video

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Background and Purpose: Alleviating pain and heaviness is the primary goal when lymphedema occurs in breast cancer patients. As the anti-inflammatory feature of chamomile on skin, we aimed to explore the effect of a chamomile compound with combined decongestive therapy (CDT) on primary outcomes including pain, volume as well as heaviness.
Source: European Journal of Cancer - Category: Cancer & Oncology Authors: Tags: POSTERS A: Supportive and Palliative Care Including End of Life Treatment Source Type: research
Authors: Southcott D, Awan A, Ghate K, Clemons M, Fernandes R Abstract Bone metastases are a significant source of morbidity and mortality for patients with breast and prostate cancer. In this review, we discuss key practical themes regarding the use of bone-targeted agents (btas) such as bisphosphonates and denosumab for managing bony metastatic disease. The btas both delay the onset and reduce the incidence of skeletal-related events (sres), defined as any or all of a need for radiation therapy or surgery to bone, pathologic fracture, spinal cord compression, or hypercalcemia of malignancy. They have more modest ...
Source: Current Oncology - Category: Cancer & Oncology Tags: Curr Oncol Source Type: research
There is a great need for physicians with competencies in Palliative Care (PC) in developing countries. In these countries, patients are often diagnosed with already advanced illness (e.g., up to 80% of breast cancer patients in developing countries versus 30% in developed countries). 80% of the global deaths occur in these countries.
Source: Journal of Pain and Symptom Management - Category: Palliative Care Authors: Source Type: research
CONCLUSIONS: Telephone interventions provide a convenient way of supporting self-management of cancer-related symptoms for adults with cancer. These interventions are becoming more important with the shift of care closer to patients' homes, the need for resource/cost containment, and the potential for voluntary sector providers to deliver healthcare interventions. Some evidence supports the use of telephone-delivered interventions for symptom management for adults with cancer; most evidence relates to four commonly experienced symptoms - depression, anxiety, emotional distress, and fatigue. Some telephone-delivered interve...
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: Tags: Cochrane Database Syst Rev Source Type: research
Palliative care providers are consulted frequently to manage complex symptoms in medically complex patients. Supportive care of patients with hormone-receptor positive breast cancer often involves consideration of ongoing medical therapy such as tamoxifen. Tamoxifen is an estrogen-receptor modulator with known association with mood disturbances, hot flashes, and fatigue. As palliative care providers, we must be aware of how to optimally manage these challenging symptoms while avoiding drug-drug interactions that could negatively impact the disease prognosis.
Source: Journal of Pain and Symptom Management - Category: Palliative Care Authors: Tags: Letter Source Type: research
CONCLUSION: We present a case that underlines the importance of specialized PC assessment not limited to the control of symptoms. The search for the etiopathogenesis of a patient's symptoms and the evaluation of overall clinical conditions may be necessary to plan appropriate diagnostic evaluations, target palliative therapies, and achieve effective symptom control. PMID: 32008478 [PubMed - as supplied by publisher]
Source: Tumori - Category: Cancer & Oncology Tags: Tumori Source Type: research
CONCLUSION: HRQoL was maintained on abemaciclib plus fulvestrant. Alongside superior PFS and manageable safety profile, results support treatment with abemaciclib plus fulvestrant in a population of patients with endocrine-resistant HR+, HER2-negative ABC. IMPLICATIONS FOR PRACTICE: In MONARCH 2, abemaciclib plus fulvestrant demonstrated superior efficacy and a manageable safety profile for patients with in hormone receptor-positive (HR+), HER2-negative (-) advanced breast cancer (ABC). Impact on health-related quality of life (HRQoL) is important to consider, given the palliative nature of ABC treatment. In this stud...
Source: The Oncologist - Category: Cancer & Oncology Authors: Tags: Oncologist Source Type: research
Conclusion: This RCT shows that perioperative pregabalin may not have a role in the prevention of chronic pain after breast surgeries.
Source: Indian Journal of Palliative Care - Category: Palliative Care Authors: Source Type: research
by Drew Rosielle (@drosielle)A Series of Observations on Opioids By a Palliative Doc Who Prescribes A Lot of Opioids But Also Has Questions.This is the 5th post in a series about opioids, with a focus on how my thinking about opioids has changed over the years. See also:Part 1 – Introduction, General Disclaimers, Hand-Wringing, and a Hand-Crafted Graph.Part 2 – We Were Wrong 20 years Ago, Our Current Response to the Opioid Crisis is Wrong, But We Should Still Be Helping Most of our Long-Term Patients Reduce Their Opioid DosesPart 3 – Opioids Have Ceiling Effects, High-Doses are Rarely Therapeutic, and Ano...
Source: Pallimed: A Hospice and Palliative Medicine Blog - Category: Palliative Care Tags: cancer opioids pain rosielle The profession Source Type: blogs
ConclusionsThis study supports previous findings that higher performance status, cancer diagnosis and higher baseline pain intensity predict analgesic RT response. The study presents new data showing that presence of soft tissue expansion predicts RT response and that CRP is not significantly associated with analgesic RT response.Clinical trial identificationNCT02107664 (Date of registration April 8, 2014).Legal entity responsible for the studyP ål Klepstad.FundingThe European Palliative Care Research Centre (PRC).DisclosureAll authors have declared no conflicts of interest.
Source: Annals of Oncology - Category: Cancer & Oncology Source Type: research
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