Decellularized bovine placentome for portacavally-interposed heterotopic liver transplantation in rats.

CONCLUSIONS: Cow placentomes will allow therapeutic development with disease models in small animals. This will also advance drug or toxicology studies. Portasystemic interposition of engineered liver will be particularly suitable for treating hepatic insufficiencies (metabolic, secretory or detoxification needs), including for children or smaller adults.
PMID: 30678914 [PubMed - in process]

Source: Appl Human Sci - January 28, 2019 Category: Physiology Authors: Kakabadze Z, Karalashvili L, Chakhunashvili D, Havlioglu N, Janelidze M, Kakabadze A, Sharma Y, Gupta S Tags: Mater Sci Eng C Mater Biol Appl Source Type: research