CBD oil: British man explains why he switched painkillers for CBD oil to manage arthritis

CBD oil is a hot topic in the world of medicine at the moment, being hailed for having various health benefits that traditional medicines lack. One British man who suffers from arthritis has ditched the use of painkillers for CBD oil, which he says is more effective in treating symptoms of the joint condition.
Source: Daily Express - Health - Category: Consumer Health News Source Type: news

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In conclusion, modulation of miR‑145‑5p expression is potentially useful for the treatment of RA inflammation, by regulating the expression of MMPs, and MMP‑9 in particular, through inhibition of the NF‑κB pathway. PMID: 31322192 [PubMed - as supplied by publisher]
Source: Molecular Medicine Reports - Category: Molecular Biology Tags: Mol Med Rep Source Type: research
Conclusions: The improvements in PsA related functional impairment could lead to sizable productivity effects within the economy. PMID: 31322444 [PubMed - as supplied by publisher]
Source: Expert Review of Pharmacoeconomics and Outcomes Research - Category: Health Management Tags: Expert Rev Pharmacoecon Outcomes Res Source Type: research
CONCLUSION: Tofacitinib did not require dose modification or restrictions for age, body weight, sex, race, ethnicity, or baseline disease severity in patients with active PsA based on the magnitude of exposure relative to a reference patient. Dosing adjustments for renal impairment were derived from a separate phase 1 study.
. PMID: 31319908 [PubMed - as supplied by publisher]
Source: International Journal of Clinical Pharmacology and Therapeutics - Category: Drugs & Pharmacology Tags: Int J Clin Pharmacol Ther Source Type: research
Conclusion. EA on ST36 and GB39 acupoints can effectively inhibit synovial angiogenesis in the AA rat model via downregulating HIF-1α/VEGF expression. PMID: 31316573 [PubMed]
Source: Evidence-based Complementary and Alternative Medicine - Category: Complementary Medicine Tags: Evid Based Complement Alternat Med Source Type: research
CONCLUSIONS This study suggested that the TT genotype and T allele in rs17221959 decreased RA risk. Smoking could decrease the protective effect of TT. PMID: 31316048 [PubMed - in process]
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
Knee pain due to arthritis or injury is the second most common cause of chronic pain in the United States. Osteoarthritis affects more than 30 million adults in the United States. And the rate of anterior cruciate ligament (ACL) tears among children and teens has been increasing about 2.3% per year for the past two decades, according to a new study. The specific cause of a patient’s knee pain has always been difficult to determine because diagnostic tools such as x-ray or MRI only image the joint in a static standing or lying down position, not in motion when the patient is feeling pain. â€...
Source: MDDI - Category: Medical Devices Authors: Tags: Orthopedics Source Type: news
Authors: Dalal A PMID: 31315345 [PubMed - in process]
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
Authors: Jagdish RK, Shailly, Bhatnagar MK PMID: 31315331 [PubMed - in process]
Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
AbstractObjectivesTo develop and evaluate an illustrated, stand-alone, interactive evidence-based shared decision making (SDM) aid for JIA children; its ability to produce positive perceived involvement of JIA patients in their own management and its impact on their adherence to therapy, school absenteeism and treatment outcomes.MethodsThe SDM aid was developed to offer information about the disease, risks and benefits of treatment. A multidisciplinary team defined SDM criteria based on international standards (IPDAS). Eight categories emerged as highly important for SDM. Each category was supported by simple illustrations...
Source: Clinical Rheumatology - Category: Rheumatology Source Type: research
Conclusions: These findings demonstrate that: 1) TNF-Tg mice display a restrictive pathology, and 2) in vivo µCT is a valid outcome measure to infer changes in pulmonary mechanical and functional parameters. PMID: 31318607 [PubMed - as supplied by publisher]
Source: Experimental Lung Research - Category: Respiratory Medicine Tags: Exp Lung Res Source Type: research
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