Mitral Valve Endocarditis: A rare Manifestation of Lyme Disease

We describe a case of mitral regurgitation with a preoperative diagnosis of myxomatous mitral valve degeneration. During surgery, the surgeon suspected infective rather than degenerative; etiology; tissue cultures were negative. However, universal bacterial PCR on explanted valve tissue detected Borrelia burgdorferi Deoxyribonucleic Acid(DNA). If a surgeon suspects infective endocarditis at the time surgery, appropriate specimens should be sent for histopathology, culture, and PCR.
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research

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Publication date: Available online 13 February 2020Source: Journal of Global Antimicrobial ResistanceAuthor(s): Pengtao Bao, Zengzhen Zhang, Weiguo Zhao, Ying Jiang, Di Wang
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
We report a case of culture ‐negative aortic valve endocarditis secondary toTropheryma whipplei infection. Our patient underwent aortic valve replacement after 4 weeks of antibiotic therapy with persistently negative blood culture results. Despite a technically uneventful operation, the patient showed continued sepsis and was unresponsive to a broad ‐spectrum of antibiotic therapy with subsequent multiorgan failure. He died on the 5th postoperative day, and diagnosis was established at postmortem examination. In this case report, we discuss the diagnosis and treatment of a rare type of endocarditis caused byT.whipplei.
Source: Journal of Cardiac Surgery - Category: Cardiovascular & Thoracic Surgery Authors: Tags: CASE REPORT Source Type: research
In this study, when the distribution of virulence genes were compAred with the isolates that have weak, medium and strong biofilm, all of the studied genes were found to be more abundant in isolates with strong and medium positive biofilm production. This has shown that excluding fimH gene, csgA, csuE and ompA genes have contributed to the biofilm formation in invasive A.baumannii isolates, respectively. PMID: 32050877 [PubMed - in process]
Source: Mikrobiyoloji Bulteni - Category: Microbiology Tags: Mikrobiyol Bul Source Type: research
AbstractThe aim of the study was to evaluate the ability to detect extra-cardiac foci by means of whole-body18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) in patients with definite endocarditis (IE) according to the modified Duke criteria and investigate the clinical impact of the findings. From January 2011 to December 2015 we included 178 patients (mean age 66  ± 14 years, 25% female) with IE in this multicentre study. FDG-PET/CT was part of the work-up for extra-cardiac foci in the including hospitals and was performed at a median of 9 days (IQR 10) af...
Source: The International Journal of Cardiovascular Imaging - Category: Radiology Source Type: research
ConclusionsIntraoperative hemoadsorption might reduce the incidence of postoperative sepsis and sepsis-related death. Additionally, patients with intraoperative hemoadsorption showed greater hemodynamic stability. These data suggest that intraoperative hemoadsorption may improve surgical outcome in patients with mitral valve endocarditis.Graphical abstract
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
Publication date: Available online 12 February 2020Source: The Annals of Thoracic SurgeryAuthor(s): Fausto Biancari., Antti Valtola, Tatu Juvonen, Annastiina Husso, Sebastian Dahlbacka, Teemu Laakso, Maina P. Jalava, Tuomas Tauriainen, Tuomas Ahvenvaara, Eeva-Maija Kinnunen, Matti Niemelä, Timo Mäkikallio, Markku Eskola, Marko P.O. Virtanen, Pasi Maaranen, Stefano Rosato, Vesa Anttila, Antti Vento, Juhani Airaksinen, Peter RaivioAbstractBackgroundRecent surgical bovine pericardial prostheses are widely used in spite of limited data on their long-term durability.MethodsThis is a comparative analysis of the outcome...
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
Infective endocarditis (IE) is a relatively rare disease with frequent fatal outcome and devastating morbidity, with a long “intubation” period, in the sense that patients harboring IE-predisposing factors (congenital and rheumatic or other acquired heart diseases with valvular abnormalities, implanted artificial and biological valves and cardiac electronic devices, etc) may develop the disease decades after exposure to such factors. Antibiotic prophylaxis (AP) is recommended prior to invasive procedures (e.g.
Source: The American Journal of Cardiology - Category: Cardiology Authors: Source Type: research
Lyme disease (LD) is an increasing public health threat in temperate zones of the northern hemisphere, yet relatively few methods exist for reducing LD risk in endemic areas. Disrupting the LD transmission cyc...
Source: Parasites and Vectors - Category: Microbiology Authors: Tags: Research Source Type: research
Source: Journal of Nuclear Cardiology - Category: Nuclear Medicine Source Type: research
Publication date: Available online 11 February 2020Source: IDCasesAuthor(s): Sho Nishimura, Sonoko Matsuyama, Keiko YamamotoAbstractStaphylococcus saprophyticus is a common pathogen associated with uncomplicated urinary tract infection in young women and commonly colonizes in the lower gastrointestinal tract as commensal bacterium. Bacteremia or infective endocarditis caused by S. saprophyticus has rarely been reported, and in almost all cases reported of bacteremia, it originated from the urinary tract or intravascular catheter-related infections. Herein, we report the case of a 77-year-old woman diagnosed with S. saproph...
Source: IDCases - Category: Infectious Diseases Source Type: research
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