Use of Mannitol for Ischemia Reperfusion Injury in Kidney Transplant and Partial Nephrectomies —Review of Literature

AbstractPurpose of ReviewFew procedures involve the ischemia-reperfusion injury to organs purposely. Two clear examples in urologic surgery consist on kidney transplantation and partial nephrectomies.Recent FindingsMannitol is an osmotic diuretic that is commonly used in partial nephrectomies and kidney transplantation to increase renal blood flow and decrease warm-ischemia-related renal injury to preserve estimated glomerular filtration rate (eGFR).SummaryWe review the current evidence for the use of mannitol and its effects on these procedures.
Source: Current Urology Reports - Category: Urology & Nephrology Source Type: research