Interest of Pan-capsule in Symptomatic Patients Suspected of Irritable Bowel Syndrome Requiring Colonoscopy

Condition:   Irritable Bowel Syndrome With Diarrhea Intervention:   Other: Pan Capsule and colonoscopy in patients with IBS Sponsors:   Hospital Avicenne;   Adeprina Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials

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Linda Ann Sasser has had ulcerative colitis since she was 20, but it wasn’t until May 2019, about 30 years later, that her condition hit a low point: not only did she have a major flare-up of chronic inflammatory bowel disease (IBD), but on top of it, she had Clostridioides difficile (or C. diff), a highly contagious bacterial infection that causes severe diarrhea and inflammation of the colon. “I became really, really sick with bloody diarrhea 30 times a day and chronic stomach pain,” Sasser says. While hospitalized for 12 days, she was given oral steroid medications, which didn’t help, then IV ste...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Disease feature Source Type: news
Laboratory studies have demonstrated that antibiotic use in conjunction with bowel purgatives causes alterations to the gut microbiota. Because gut microbiota changes may be a trigger for the development of irritable bowel syndrome (IBS), we sought to assess whether individuals who undergo bowel cleansing for colonoscopy and have concurrent antibiotic exposure develop IBS at higher rates than individuals who undergo colonoscopy without antibiotic exposure.
Source: Clinical Gastroenterology and Hepatology - Category: Gastroenterology Authors: Source Type: research
We examined the yield of colonoscopy and upper endoscopy in IBS for several organic diseases.METHODS: Matched population-based prevalence study in Sweden. We identified 21,944 participants diagnosed with IBS from 1987 to 2016 undergoing colonoscopy with a biopsy from all of Sweden's 28 pathology departments within 6 months of diagnosis. We compared prevalence of histopathology-proven diagnoses of inflammatory bowel disease (IBD), colorectal cancer, precancerous polyps, and microscopic colitis between patients recently diagnosed with IBS and matched controls without IBS (n = 81,101) undergoing colonoscopy. We also compared ...
Source: European Journal of Internal Medicine - Category: Internal Medicine Authors: Source Type: research
Ultrasound, MIR [MRI], CAT scan [CT], sonogram,Laparoscopy, inoscopy [colonoscopy], I be stressed,The prognosis, diagnosis, IBSAnd that ’s irritable bowel child—I.B.S. by Cam’ron from the Killa Season album (2006)Yes, irritable bowel syndrome (IBS) has been written about, sung about, and rapped about. It’s only one letter away from IBD, but in reality, actually a world away, although patients with IBS may have IBD and vice v ersa, and as such, clinicians may sometimes be treating the right problem at the wrong time or the wrong problem at the wrong time.
Source: Gastroenterology Clinics of North America - Category: Gastroenterology Authors: Source Type: research
Curr Drug Targets. 2021 Jul 7. doi: 10.2174/1389450122666210707122151. Online ahead of print.ABSTRACTLipidomics is an emerging and promising branch that analyses the different lipid mole-cules in a biological sample. It is considered a branch of metabolomics, which is defined as the comprehensive analysis of metabolites in a biological specimen. Nonetheless, in recent years lipidomics is becoming a distinct discipline in the biomedicine field. Lipids play important roles in many biological pathways and can work as biomarkers of disease or therapeutic targets for the treatment of diseases. The major lipidomics strategies ar...
Source: Current Drug Targets - Category: Drugs & Pharmacology Authors: Source Type: research
We report a case of a 35-year-old African American man with a past medical history of IBS who presented to the clinic with a chief complaint of abdominal pain and bloody diarrhea for 1 week. The patient stated that he used a colon-cleansing agent because of persistent constipation. Computed tomography scan of the patient ’s abdomen and pelvis with contrast was performed which showed diffuse contiguous segmental mural thickening and nodularity seen along the distal transverse, descending, and sigmoid colon. Colonoscopy showed moderate diffuse inflammation characterized by altered vascularity, erythema, and granular it...
Source: Case Reports in Gastroenterology - Category: Gastroenterology Source Type: research
World J Gastroenterol. 2021 Mar 7;27(9):760-781. doi: 10.3748/wjg.v27.i9.760.ABSTRACTDiverticular disease and diverticulitis are the most common non-cancerous pathology of the colon. It has traditionally been considered a disease of the elderly and associated with cultural and dietary habits. There has been a growing evolution in our understanding and the treatment guidelines for this disease. To provide an updated review of the epidemiology, pathogenesis, classification and highlight changes in the medical and surgical management of diverticulitis. Diverticulitis is increasingly being seen in young patients (
Source: World Journal of Gastroenterology : WJG - Category: Gastroenterology Authors: Source Type: research
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