Concurrent Radiation and Immunotherapy: Survey of Practice Patterns in the United States

The objective of this study was to report on US radiation oncologists’ (ROs) practice patterns and perceptions of concurrent radiation (RT) and immunotherapy (IT) (CRI). Methods: A 22-question survey was emailed to radiation oncologists in February 2018. CRI was defined as RT completed within 1 week before initial IT infusion through 4 weeks after final IT infusion. Results: Of the 323 respondents from 45 states, 88% had experience treating a patient with CRI, including 51% private and 48% academic physicians. The most common reason for not offering CRI was concerns of increased toxicity (50%). Although 84% to 94% of respondents did not change RT dose, more ROs decreased dose when treating central structures (chest/abdomen/pelvis) versus noncentral structures (brain/head and neck/extremities): 13% to 15% versus 4% to 8%, P
Source: American Journal of Clinical Oncology - Category: Cancer & Oncology Tags: Original Articles: Experimental Therapeutics Source Type: research