Increased expression of brain-derived neurotrophic factor is correlated with visceral hypersensitivity in patients with diarrhea-predominant irritable bowel syndrome.

CONCLUSION: Elevated mucosal BDNF may participate in the pathogenesis of IBS-D via facilitating mucosal nerve growth and increasing visceral sensitivity.
PMID: 30670915 [PubMed - in process]

Source: World Journal of Gastroenterology : WJG - January 14, 2019 Category: Gastroenterology Authors: Zhang Y, Qin G, Liu DR, Wang Y, Yao SK Tags: World J Gastroenterol Source Type: research