Smoking tied to vascular disease risk in African-Americans

CT coronary artery calcium scans of African-Americans revealed that smoking...Read more on AuntMinnie.comRelated Reading: CT CAC reveals high heart disease risk in South Asian men CCTA reveals statins may lower mortality in low-risk CAD USPSTF dismisses CAC for heart disease risk assessment How often are lung nodules missed on CAC scoring scans? Iterative recon halves CT radiation dose for calcium score
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news

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We examined human lung tissue from COPD patients and normal control subjects, and found a substantial increase in p16-expressing alveolar cells in COPD patients. Using a transgenic mouse deficient for p16, we demonstrated that lungs of mice lacking p16 were structurally and functionally resistant to CS-induced emphysema due to activation of IGF1/Akt regenerative and protective signaling. Fat Tissue Surrounds Skeletal Muscle to Accelerate Atrophy in Aging and Obesity https://www.fightaging.org/archives/2019/09/fat-tissue-surrounds-skeletal-muscle-to-accelerate-atrophy-in-aging-and-obesity/ Researchers her...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Authors: Alves-Ferreira J, Rocha-Neves J, Dias-Neto M, F Braga S Abstract Objetives: Carotid endarterectomy (CEA) is an established treatment for carotid stenosis (CS). However, this procedure is not risk-free and it is insufficient to control disseminated atherosclerosis. Our aim was to determine long-term cardiovascular (CV) morbidity and mortality after CEA and identify associated risk predictors. DESIGN: Consecutive cohorts of CEAs performed between 2010-2018 in two Portuguese hospitals were retrospectively analysed. The major end-points were acute myocardial infarction (AMI), stroke, all-cause death and ma...
Source: Scandinavian Cardiovascular Journal - Category: Cardiology Tags: Scand Cardiovasc J Source Type: research
Conclusion: This study suggests that a clinically efficacious cardiovascular Chinese herbal medicine (DLP) can be successfully repurposed to treat a lung disease in pulmonary fibrosis guided by TCM theory. Our comparative study between DLP and DHP demonstrated a critical requirement of suppressing both pro-inflammatory and pro-fibrotic pathways for the treatment of pulmonary fibrosis, supporting that a multi-component prescription capable of “removing both phlegm and blood stasis” will better achieve co-protection of heart and lung in PHD. Introduction Idiopathic pulmonary fibrosis (IPF) is a chronic an...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Conclusions: Embolism associated with asymptomatic carotid stenosis shows circadian variation with highest rates 4–6 h before midday. This corresponds with peak circadian incidence of stroke and other vascular complications. These and ASED Study results show that monitoring frequency, duration, and time of day are important in ES detection. Introduction Transcranial Doppler (TCD) detected microembolism in the ipsilateral middle cerebral artery (MCA) may help stratify the risk of stroke and other arterial disease complications in persons with advanced (≥60%) asymptomatic carotid stenosis. If so, this techniqu...
Source: Frontiers in Neurology - Category: Neurology Source Type: research
Coronary artery calcium (CAC) scores from CT scans could help inform treatment...Read more on AuntMinnie.comRelated Reading: Could self-rated health improve CT CAC scoring? Heart societies endorse CT CAC for risk assessment High CT CAC scores in athletes do not increase mortality CT CAC reveals high heart disease risk in South Asian men CCTA reveals statins may lower mortality in low-risk CADComments: 3/8/2019 6:10:01 AMJ Shea The author suggests CaSc is free information. That's true on some level but the study isn't obtained in the same way and also requires post-processing. Adding a score to every chest CT is...
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
You won’t hear silly, ineffective nonsense like “cut your saturated fat,” or “move more, eat less,” “everything in moderation,” or “take a statin drug” around here—you know, the advice that keeps heart disease the #1 killer of Americans and keeps doctors and hospital busy making plenty of money. Here are the strategies that I used for many years in thousands of patients based on published (but often under appreciated) science that achieved reversal of heart disease in the majority. The post Ten ways to reduce or eliminate heart disease risk appeared first on Dr. William Davis.
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: News & Updates cholesterol coronary grain-free heart disease heart scan undoctored wheat belly Source Type: blogs
The incidence and progression rates of coronary artery calcium (CAC) on the...Read more on AuntMinnie.comRelated Reading: CCTA reveals statins may lower mortality in low-risk CAD USPSTF dismisses CAC for heart disease risk assessment ACC: PET/CT calcium scans could foretell cardiac events How often are lung nodules missed on CAC scoring scans? JACC: CT CAC scoring helps screen for CAD
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
Just before Mother’s Day, I was a guest on an Al-Jazeera news segment focused on the challenges of aging in America. It was my first-ever news appearance, and, later, I proudly showed a recording to my adult daughters when they came by to visit. The segment included a look at how elders are navigating the shoals of old age, sickness, and financial insecurity—a future millions of face, and all of us deny. One segment featured a mid-life African American woman who had abandoned her retirement dreams to care for her mother, who has Alzheimer’s. As the woman fixed her mother’s wisps of hair, both daught...
Source: Disruptive Women in Health Care - Category: Consumer Health News Authors: Tags: Uncategorized Source Type: blogs
This study indicates that frailty and other age-related diseases could be prevented and significantly reduced in older adults. Getting our heart risk factors under control could lead to much healthier old ages. Unfortunately, the current obesity epidemic is moving the older population in the wrong direction, however our study underlines how even small reductions in risk are worthwhile." The study analysed data from more than 421,000 people aged 60-69 in both GP medical records and in the UK Biobank research study. Participants were followed up over ten years. The researchers analysed six factors that could impa...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Conclusion: Both LDL-C and inflammation reduction are beneficial to the reduction of CVD risk. However, canakinumab is a very expensive drug that only induced a 15% reduction in CVD events, thus drastically reducing the possibility for it to be used in clinical practice. Besides, canakinumab is associated with increased infections, some fatal. A potent statin with anti-inflammatory effects is probably the best choice for the majority of those needing hypolipidaemic drug therapy. PMID: 29785212 [PubMed]
Source: Open Cardiovascular Medicine Journal - Category: Cardiology Tags: Open Cardiovasc Med J Source Type: research
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