Smoking tied to vascular disease risk in African-Americans

CT coronary artery calcium scans of African-Americans revealed that smoking...Read more on AuntMinnie.comRelated Reading: CT CAC reveals high heart disease risk in South Asian men CCTA reveals statins may lower mortality in low-risk CAD USPSTF dismisses CAC for heart disease risk assessment How often are lung nodules missed on CAC scoring scans? Iterative recon halves CT radiation dose for calcium score
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news

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By KEN TERRY (This is the eighth and final installment in a series of excerpts from Terry’s new book, Physician-Led Healthcare Reform: a New Approach to Medicare for All, published by the American Association for Physician Leadership.) Medical technologies include drugs, devices, tests, and procedures. Considered as a whole, these technologies are the key driver of growth in health costs, according to Georgetown University professor Gregg Bloche and his associates. Bloche, et al., view insurance coverage as the chief enabler of these technological innovations. In a 2017 Health Affairs Blog post, they sai...
Source: The Health Care Blog - Category: Consumer Health News Authors: Tags: Health Policy Ken Terry Source Type: blogs
This study provides characterization of a lipid-rich necrotic core, a dangerous type of coronary plaque made up of dead cells and cell debris that is prone to rupture. Ruptured plaque can lead to a heart attack or stroke. The analysis involved 209 middle-aged patients (ages 37-62) with psoriasis who participated in the Psoriasis Atherosclerosis Cardiometabolic Initiative at the National Institutes of Health, an ongoing observational study. Of these participants, 124 received biologic therapy, and 85 were in the control group, treated only with topical creams and light therapy. To measure the effects of biologic ther...
Source: Fight Aging! - Category: Research Authors: Tags: Daily News Source Type: blogs
In this study, we sought to elucidate the role of VRK-1 in regulation of adult life span in C. elegans. We found that overexpression of VRK-1::GFP (green fluorescent protein), which was detected in the nuclei of cells in multiple somatic tissues, including the intestine, increased life span. Conversely, genetic inhibition of vrk-1 decreased life span. We further showed that vrk-1 was essential for the increased life span of mitochondrial respiratory mutants. We demonstrated that VRK-1 was responsible for increasing the level of active and phosphorylated form of AMPK, thus promoting longevity. A Fisetin Variant, C...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
If you have a CT heart scan score (also called coronary calcium score), what effect do statin cholesterol drugs have on stopping or slowing the increase in score? (Increasing scores pose increasing risk for heart attack and other cardiac events.) NONE. If you do nothing at all, the score increases by 25% per year, on average. If you take a statin drug, aspirin, and follow a low-fat diet, what my colleagues call “optimal medical therapy,” the score increases . . . 25% per year—no difference. Yet this is the “solution” that conventional doctors push on their patients, a “treatment” t...
Source: Wheat Belly Blog - Category: Cardiology Authors: Tags: Open cholesterol coronary calcium ct scan do statin drugs reduce heart scan scores reduce coronary calcium reverse coronary calcium reverse heart disease undoctored wheat belly Source Type: blogs
High levels of plaque calcification on coronary CT angiography (CCTA) scans...Read more on AuntMinnie.comRelated Reading: CCTA, functional tests stratify heart disease risk by age Onsite FFR-CT tops CCTA in detecting coronary stenosis CCTA reveals statins may lower mortality in low-risk CAD CCTA biomarker may predict mortality from heart disease CCTA biomarker spots high-risk plaques in heart disease
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
Researchers are using artificial intelligence to measure a common marker of heart disease via lung cancer screenings. The research was presented at the annual meeting of the Radiological Society of North America (RSNA). Low-dose chest CT is approved for lung cancer screening in high-risk people, such as long-time smokers. While these CT scans are intended to diagnose lung cancer, coronary artery calcium, a measure of plaque in the arteries, is also visible on CT. The coronary artery calcium score derived from CT is a well-established measure that helps doctors decide who should get cholesterol-lowering preventive medicatio...
Source: MDDI - Category: Medical Devices Authors: Tags: Digital Health IVD Source Type: news
The combination of coronary CT angiography (CCTA) scans and functional tests...Read more on AuntMinnie.comRelated Reading: FFR-CT beats CCTA for assessing heart disease outcomes CCTA reveals statins may lower mortality in low-risk CAD CCTA biomarker may predict mortality from heart disease SCOT-HEART: CCTA cuts risk of heart attack, death by 41% CCTA biomarker spots high-risk plaques in heart disease
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
We examined human lung tissue from COPD patients and normal control subjects, and found a substantial increase in p16-expressing alveolar cells in COPD patients. Using a transgenic mouse deficient for p16, we demonstrated that lungs of mice lacking p16 were structurally and functionally resistant to CS-induced emphysema due to activation of IGF1/Akt regenerative and protective signaling. Fat Tissue Surrounds Skeletal Muscle to Accelerate Atrophy in Aging and Obesity https://www.fightaging.org/archives/2019/09/fat-tissue-surrounds-skeletal-muscle-to-accelerate-atrophy-in-aging-and-obesity/ Researchers her...
Source: Fight Aging! - Category: Research Authors: Tags: Newsletters Source Type: blogs
Authors: Alves-Ferreira J, Rocha-Neves J, Dias-Neto M, F Braga S Abstract Objetives: Carotid endarterectomy (CEA) is an established treatment for carotid stenosis (CS). However, this procedure is not risk-free and it is insufficient to control disseminated atherosclerosis. Our aim was to determine long-term cardiovascular (CV) morbidity and mortality after CEA and identify associated risk predictors. DESIGN: Consecutive cohorts of CEAs performed between 2010-2018 in two Portuguese hospitals were retrospectively analysed. The major end-points were acute myocardial infarction (AMI), stroke, all-cause death and ma...
Source: Scandinavian Cardiovascular Journal - Category: Cardiology Tags: Scand Cardiovasc J Source Type: research
Conclusion: This study suggests that a clinically efficacious cardiovascular Chinese herbal medicine (DLP) can be successfully repurposed to treat a lung disease in pulmonary fibrosis guided by TCM theory. Our comparative study between DLP and DHP demonstrated a critical requirement of suppressing both pro-inflammatory and pro-fibrotic pathways for the treatment of pulmonary fibrosis, supporting that a multi-component prescription capable of “removing both phlegm and blood stasis” will better achieve co-protection of heart and lung in PHD. Introduction Idiopathic pulmonary fibrosis (IPF) is a chronic an...
Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
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