Predicting Lab Values for Gastrointestinal Bleeding Patients in the Intensive Care Unit: A Comparative Study on the Impact of Comorbidities and Medications

Publication date: Available online 23 January 2019Source: Artificial Intelligence in MedicineAuthor(s): Golnar K. Mahani, Mohammad-Reza PajoohanAbstractSince a significant number of frequent laboratory blood tests are unnecessary and these tests may have complications, developing a system that could identify unnecessary tests is essential. In this paper, a value prediction approach is presented to predict the values of Calcium and Hematocrit laboratory blood tests for upper gastrointestinal bleeding patients and patients with unspecified hemorrhage in their gastrointestinal tract. The data have been extracted from the MIMIC-II database. By considering the issues of MIMIC-II in the process of data extraction and using expert knowledge, comprehensive preprocessing has been performed to validate the data. The first prediction system is developed using zero order Takagi-Sugeno fuzzy modeling and the sequential forward selection method. The results of this prediction system for target laboratory tests are promising. In the second proposed prediction system, patients are clustered using their comorbidity information before the final prediction phase. For each cluster, a medication feature is constructed and added to the data for the final feature selection. Although it was expected that clustering patients based on comorbidity data could improve the results of value prediction, the results were not improved in average. The reason for this could be the small number of abnormal labor...
Source: Artificial Intelligence in Medicine - Category: Bioinformatics Source Type: research

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This article provides a critical appraisal of both past and present data for aspirin in the primary prevention setting. PubMed and Cochrane Central Register databases were searched from inception to May 1st, 2019. Expert opinion: The decision to initiate or withdraw aspirin for primary prevention requires an understanding of the equilibrium between efficacy and safety. In adults greater than 70 years of age, low to moderate cardiovascular risk, controlled diabetes, or at high risk of bleeding, initiation of aspirin for primary prevention should generally be avoided. Instead, risk factor modification should be prioritized. ...
Source: Expert Review of Cardiovascular Therapy - Category: Cardiology Tags: Expert Rev Cardiovasc Ther Source Type: research
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Source: Scandinavian Journal of Gastroenterology - Category: Gastroenterology Tags: Scand J Gastroenterol Source Type: research
We report retrospective data on Dutch ruxolitinib-treated myelofibrosis patients, focusing on those with baseline thrombocytopenia. Additionally, we reviewed current literature regarding ruxolitinib treatment in this subgroup.ResultsIn our cohort, 12/119 patients had a baseline platelet count
Source: Clinical Lymphoma Myeloma and Leukemia - Category: Cancer & Oncology Source Type: research
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Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
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Source: Journal of the Association of Physicians of India - Category: General Medicine Tags: J Assoc Physicians India Source Type: research
Think back to your childhood at a point when you scraped your knee. You had two options: Clean it up and let it air out or place a bandage over it to stop the bleeding. Which recovery method was truly the most effective? Contrary to popular belief, giving a wound time to breathe without a dressing doesn't improve healing time. In fact, it may induce pain and even slow down the healing process. What happens when you leave a wound uncovered If we think far back to before the bandage was invented, men and women likely let their cuts and scrapes be if there wasn't a form of dressing available. They discovered that the ...
Source: Advanced Tissue - Category: Dermatology Authors: Tags: Wound Care Source Type: news
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Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
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