New IgE Immediate Hypersensitivity Reactions Upon Reintroduction of Food Restricted for Treatment of Eosinophilic Esophagitis

Eosinophilic esophagitis (EoE) is a chronic immune mediated disease. As EoE is largely food driven, elimination diets (ED) are one of the two primary modalities used to treat EoE 1,2 Options include empiric EDs (6, 4, or 2 food EDs) or targeted EDs based on food allergy testing.3,4 Recently, children with EoE have been reported to develop immediate hypersensitivity reactions with reintroduction of previously IgE tolerated milk.5,6,7,8 Herein, anaphylaxis to previously tolerated wheat in an adult with EoE, and diffuse urticaria from soy reintroduction in a teen with EoE are presented.

Source: Annals of Allergy, Asthma and Immunology - January 23, 2019 Category: Allergy & Immunology Authors: Steven J. Gottlieb, Jonathan E. Markowitz, Evan S. Dellon Tags: Letters Source Type: research