Utilizing genomic analyses to investigate the first outbreak of vanA vancomycin-resistant Enterococcus in Australia with emergence of daptomycin non-susceptibility.

CONCLUSIONS: Here we describe an outbreak of vanA VREfm in a haematology/oncology unit. Genomic analysis supports transmission of an ST203 vanA VRE clone within this unit. Daptomycin non-susceptibility in 5/24 patients left linezolid as the only treatment option. Daptomycin susceptibility cannot be assumed in vanA VREfm isolates and confirmatory testing is recommended. PMID: 30663951 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30663951?dopt=Abstract

Source: Journal of Medical Microbiology - January 21, 2019 Category: Microbiology Authors: Douglas AP, Marshall C, Baines SL, Ritchie D, Szer J, Madigan V, Chan HT, Ballard SA, Howden BP, Buising K, Slavin MA Tags: J Med Microbiol Source Type: research