Early blastocyst expansion in euploid and aneuploid human embryos: evidence for a non-invasive and quantitative marker for embryo selection

ConclusionsThe kinetics of human blastocyst expansion do correlate with an embryo's ploidy. These preliminary observations describe a new quantitative, non-invasive approach to embryo assessment that may be useful to identify single blastocysts for transfer, particularly in younger patient groups. However, this approach may be useful for euploid embryo selection after PGT-A as well. The results support the hypothesis that aneuploidy universally impairs general cellular processes in differentiated cells, including cell division.

Source: Reproductive BioMedicine Online - January 23, 2019 Category: Reproduction Medicine Source Type: research