Lactobacillus rhamnosus GG as an Effective Probiotic for Murine Giardiasis.

Lactobacillus rhamnosus GG as an Effective Probiotic for Murine Giardiasis. Interdiscip Perspect Infect Dis. 2011;2011:795219 Authors: Goyal N, Tiwari RP, Shukla G Abstract The gut microflora is an important constituent in the intestinal mucosal barrier and has been introduced as the concept of probiotic therapy that beneficially affects the host by improving its intestinal microbial balance. Therefore, the main objective of the study was to explore the protective potential of various lactobacilli strains for murine giardiasis. By experimentation, it was found that the probiotic supplementation of either Lactobacillus casei, L. acidophilus, L. plantarum, or L. rhamnosus GG, 7 days prior to inoculation with G. lamblia trophozoites, reduced the rate of cyst excretion compared with Giardia-infected mice. Interestingly, L. GG was found to be the most effective probiotic in reducing the duration of giardia cycle and acts as an effective prophylactic probiotic for murine giardiasis but needs to be clinically correlated due to entirely different human microflora. PMID: 21760784 [PubMed]
Source: Interdisciplinary Perspectives on Infectious Diseases - Category: Infectious Diseases Tags: Interdiscip Perspect Infect Dis Source Type: research

Related Links:

AbstractPurpose of reviewHere, we review recent progress made on the genetic characterization ofGiardia duodenalis assemblages and their relationship with virulence. We also discuss the implications of virulence factors in the pathogenesis of giardiasis, and advances in the development of vaccines and drugs based on knowledge of virulence markers.Recent findingsThe use of transcriptomic and proteomic technologies as well as whole genome sequencing (WGS) from single cysts has allowed the assembly of the draft genome sequences for assemblages C and D ofG. duodenalis. These findings, along with the published genomes for assem...
Source: Current Tropical Medicine Reports - Category: Tropical Medicine Source Type: research
Conclusions: This study revealed a high prevalence of infection with at least one or six non‑pathogenic and pathogenic intestinal protozoa in UC patients in the Isfahan region. Intestinal protozoa are a challenging public health problem wherever health care is limited in the area. The emergence of UC in the world result s in the need to study etiologic factors. In order to obtain further information about the etiology of disease, we investigated the prevalence of intestinal protozoan infection in patients with UC in Isfahan, Iran.
Source: International Journal of Preventive Medicine - Category: International Medicine & Public Health Source Type: research
Captive wild animals in zoos infected with Cryptosporidium spp., Giardia duodenalis, Enterocytozoon bieneusi, and Blastocystis sp. can be sources of zoonotic infections and diseases. Therefore, to investigate the...
Source: BMC Veterinary Research - Category: Veterinary Research Authors: Tags: Research article Source Type: research
This study assessed the proteasome activity in the trophozoite and during encystation. Strong activation of the proteasome was observed during the differentiation of trophozoites into cysts, reaching its maximum level 24 hours after the stimulus. We also found that the Giardia proteasome presents unusual characteristics related to higher eukaryotic proteasomes, making it an eventual therapeutic target. Here we tested the effects on the synthesis of a cyst wall protein by chemical inactivation of the proteasome and by overexpression or partial inhibition of the deubiquitinating protein RPN11 in transfected cells. Moreover, ...
Source: Acta Tropica - Category: Infectious Diseases Authors: Source Type: research
Updated Date: Mon, 04 Oct 2021 00:00:00 EDT
Source: DailyMed Drug Label Updates - Category: Drugs & Pharmacology Source Type: alerts
Intestinal parasites (IPs) are widely distributed worldwide and are one of the major contributors to gastrointestinal disease. Their prevalence is associated with poor access to water, sanitation and hygiene (...
Source: Parasites and Vectors - Category: Microbiology Authors: Tags: Research Source Type: research
AbstractOrganic (such as parasites or vegetable remnants) and inorganic substances may be encountered during routine pathology diagnostic work up of endoscopic gastrointestinal biopsy samples and major resections, causing possible diagnostic conundrums for the young and not so young pathologists. The main aim of this review is the description of the most frequent oddities one can encounter as foreign bodies, in gastrointestinal pathology, on the basis of the current literature and personal experience. The types of encountered substances are divided into four principal categories: parasites (helminths such asEnterobius verm...
Source: Virchows Archiv - Category: Pathology Source Type: research
In conclusion, our results support a possible link between IPIs and IBD.PMID:34588367 | DOI:10.7883/yoken.JJID.2021.438
Source: Japanese Journal of Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research
More News: Acidophilus | Gastroenteritis | Giardiasis | Infectious Diseases | Lactobacillus Acidophilus | Study