Association between the IL1R2 rs2072472 polymorphism and high ‐altitude pulmonary edema risk

ConclusionThese findings suggested thatIL1R2polymorphisms may contribute to the protection of HAPE.
Source: Molecular Genetics & Genomic Medicine - Category: Genetics & Stem Cells Authors: Tags: ORIGINAL ARTICLE Source Type: research

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Abstract Preeclampsia (PE) is termed as an obstetric issue that is characterized by hypertension (≧140/90 mm Hg), together with proteinuria following 20 weeks of pregnancy. Until today, PE still constitutes a severe threat to the lives of both the mothers and fetuses. In the past, long noncoding RNAs (lncRNAs) were considered as the transcriptional noise. However, some investigations have indicated that lncRNAs could be used as innovative indicators in PE. The current review aims to discuss the relationship between lncRNAs and PE in recent years. According to the retrieved data, we concluded that lncRNAs ...
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
The objective of this study was to evaluate associations between marijuana use and the prevalence, severity, and rate of occurrence of tinnitus.Study designCross-sectional analysis of nationally representative data.SettingNational Health and Nutrition Examination Survey 2011–2012.Subjects and methodsStatistical analysis was performed on data collected from 2705 non-institutionalized adults aged 20–69 who underwent audiometric testing and were administered questionnaires about hearing, drug use, current health status, and medical history.ResultsThe use of marijuana at least once per month for the previous 12 m...
Source: American Journal of Otolaryngology - Category: Endocrinology Source Type: research
Publication date: Available online 13 November 2019Source: Pharmacological ResearchAuthor(s): Aline C. Oliveira, Elaine M. Richards, Mohan K. RaizadaAbstractPulmonary hypertension (PH) is classically considered a disease of pulmonary vasculature which has been the predominant target for drug development and pH therapy. Despite significant advancement in recent years in identification of new drug targets and innovative treatment strategies, the prognosis of pH remains poor, with median survival of 5 years. Recent studies have demonstrated involvement of neuroinflammation, altered autonomic and gastrointestinal functions and...
Source: Pharmacological Research - Category: Drugs & Pharmacology Source Type: research
Authors: Glöckl R, Schneeberger T, Boeselt T, Kenn K, Koczulla AR, Held M, Oberhoffer R, Halle M Abstract BACKGROUND:  Pulmonary hypertension (PH) is defined as an elevation of mean pulmonary-arterial pressure by> 20 mmHg at rest, which may lead to right heart failure. Physical exercise has not been regularly recommended for PH patients for fear of symptom deterioration or occurrence of exercise-induced adverse events. METHODS:  Three electronic databases were searched for randomized, controlled trials investigating exercise training in PH patients using the following keywords: "pulmo...
Source: Pneumologie - Category: Respiratory Medicine Tags: Pneumologie Source Type: research
Authors: Damaskos C, Garmpis N, Kollia P, Mitsiopoulos G, Barlampa D, Drosos A, Patsouras A, Gravvanis N, Antoniou V, Litos A, Diamantis E Abstract The globalization of the Western lifestyle has resulted in a dramatic increase of diabetes mellitus, a complex, multifactorial disease. Diabetes mellitus is a condition often associated with disorders of the cardiovascular system. It is well established that three quarters of diabetics, aged over 40, will die from cardiovascular disease and are more likely than non-diabetics to die from their first cardiovascular event. Therefore, risk stratification is necessary to ind...
Source: Current Cardiology Reviews - Category: Cardiology Tags: Curr Cardiol Rev Source Type: research
Anirban GanguliIndian Journal of Nephrology 2019 29(6):381-382
Source: Indian Journal of Nephrology - Category: Urology & Nephrology Authors: Source Type: research
Conclusions: There was no statistical significant association between any of the studied heavy metals and CKD, although there was a significant burden of heavy metals in the studied subjects.
Source: Indian Journal of Nephrology - Category: Urology & Nephrology Authors: Source Type: research
Obesity, insulin resistance, dyslipidemia, and hypertension are fundamental clinical manifestations of the metabolic syndrome. Studies over the last few decades have implicated chronic inflammation and microvascular remodeling in the development of obesity and insulin resistance. Newer observations, however, suggest that dysregulation of the lymphatic system underlies the development of the metabolic syndrome. This review summarizes recent advances in the field, discussing how lymphatic abnormality promotes obesity and insulin resistance, and, conversely, how the metabolic syndrome impairs lymphatic function. We also discu...
Source: Frontiers in Physiology - Category: Physiology Source Type: research
AbstractPurposeTo determine the efficacy of cataract surgery alone and combined with two minimally invasive glaucoma surgery (MIGS) procedures (phaco-ELT and phaco-aiT).MethodsData was collected from 12/2007 to 02/2012 in this retrospective, non-randomized, comparative single surgery center study. Reduction in IOP and hypotensive medication (AGD), change in visual acuity, success rates, and complications were computed by comparing preoperative data with data at 1  year postoperatively.ResultsA total of 245 eyes of 245 subjects were included. Study eyes underwent phaco alone (38 eye) or combined phaco-ELT (105 eye) and...
Source: International Ophthalmology - Category: Opthalmology Source Type: research
Patients may have been willing to risk the short-term potential of uncontrolled hypertension to avoid ingesting a potential carcinogen in recalled generic valsartan medications, the authors say.Medscape Medical News
Source: Medscape Cardiology Headlines - Category: Cardiology Tags: Cardiology News Source Type: news
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