EP News: Clinical

Krahn et  al (J Am Coll Cardiol 2018;72:3098–3109, PMID 30545448) evaluated the effectiveness of incremental perioperative antibiotics to reduce device infection. Using a cluster randomized crossover trial with 4 randomly assigned 6-month periods, centers used either conventional or incremental periproced ural antibiotics for all cardiac implantable electronic device procedures. Conventional treatment was preprocedural cefazolin infusion. Incremental treatment was preprocedural cefazolin plus vancomycin, intraprocedural bacitracin pocket wash, and 2-day postprocedural oral cephalexin.

Source: Heart Rhythm - January 22, 2019 Category: Cardiology Authors: N.A. Mark Estes Tags: EP News Source Type: research