Buprenorphine for the treatment of posttraumatic stress disorder.

CONCLUSIONS: Buprenorphine may help decrease PTSD symptoms more than SSRIs or opioids alone. Prospective studies are needed to determine whether these effects are reproducible.
SCIENTIFIC SIGNIFICANCE: Pharmacotherapy advancements in PTSD treatment have been limited and the kappa opioid receptor system presents a new target that warrants further research. (Am J Addict 2019;XX:1-6).
PMID: 30664299 [PubMed - as supplied by publisher]

Source: American Journal on Addictions - January 21, 2019 Category: Addiction Authors: Lake EP, Mitchell BG, Shorter DI, Kosten T, Domingo CB, Walder AM Tags: Am J Addict Source Type: research