Intranasal Treatment With 1, 25-Dihydroxyvitamin D3 Alleviates Allergic Rhinitis Symptoms in a Mouse Model.

CONCLUSIONS: The results confirm the antiallergic effect of intranasal 1,25-dihydroxyvitamin D3. It decreases CD 86 expression among CD11c⁺MHCIIhigh cells and T-helper type 2-mediated inflammation in the cervical LNs. Therefore, topically applied 1,25-dihydroxyvitamin D3 can be a future therapeutic agent for allergic rhinitis. PMID: 30661318 [PubMed]

https://www.ncbi.nlm.nih.gov/pubmed/30661318?dopt=Abstract

Source: Allergy, Asthma and Immunology Research - January 22, 2019 Category: Allergy & Immunology Tags: Allergy Asthma Immunol Res Source Type: research