Streptococcus mutans serotypes and Collagen ‐Binding Proteins Cnm/Cbm in Children with Caries analyzed by PCR

SummaryStreptococcus mutans, a primary bacterium associated with dental caries, has four known clinical serotypes (c, e, f, andk). Some serotypes, presence of multiple serotypes and strains with collagen ‐binding proteins (CBP, Cnm and Cbm) have been linked with systemic disease. Evaluation ofS. mutans serotype distribution and caries association is needed in the United States. The purpose of this study was to evaluate the prevalence ofS. mutans serotypes from two cohorts of African American children in rural Alabama using 3 sample types (saliva, plaque, and individualS. mutans isolates) by PCR detection for association with caries. Detection of CBP was also performed by PCR. In total, 129 children were evaluated and overall prevalence of serotypes were: serotypec(98%),e(26%),f(7%), andk(52%). Serotypec was statistically associated with higher caries scores in older children (p
Source: Molecular Oral Microbiology - Category: Microbiology Authors: Tags: Original Article Source Type: research

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