Mitochondrial genome sequence variation as a useful marker for assessing genetic heterogeneity among Cyclospora cayetanensis isolates and source-tracking

Cyclospora cayetanensis is an important enteric pathogen, causing diarrhea and food-borne cyclosporiasis outbreaks. For effective outbreak identification and investigation, it is essential to rapidly assess the g...
Source: Parasites and Vectors - Category: Microbiology Authors: Tags: Research Source Type: research

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It may be possible to eradicate malaria—one of history’s deadliest diseases—from the planet by 2050, according to a coalition of 41 leading scientists, economists and health-policy experts writing in the Lancet. “Malaria is one of the oldest and deadliest diseases of humankind,” says Sir Richard Feachem, one of the report’s authors and co-chair of the Lancet commission on malaria eradication. “If we, humankind, were to take on this challenge and eradicate malaria by 2050, it would be an achievement of historic proportions. There would be nothing quite like it.” Malaria, a mos...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized Infectious Disease onetime Source Type: news
Over the last decade, reports about dengue cases have increase worldwide, which is particularly worrisome in South America due to the historic record of dengue outbreaks from the seventeenth century until the ...
Source: Parasites and Vectors - Category: Microbiology Authors: Tags: Research Source Type: research
In conclusion, a risk of swimmer's itch in Denmark was confirmed. PMID: 31453626 [PubMed - as supplied by publisher]
Source: Acta Dermato-Venereologica - Category: Dermatology Authors: Tags: Acta Derm Venereol Source Type: research
Cyclospora cayetanensis is a coccidian parasite that has been associated with foodborne outbreaks of gastrointestinal illnesses. Raspberries have been implicated as vehicle of infection in some of these outbreaks. Most of the molecular techniques used for the detection of parasites commonly use the 18s rRNA as a target gene, which is highly conserved. The conserved nature of 18s rRNA gene among coccidia means that there is potential for cross-reactivity from primers intended to target this gene in C. cayetanensis with the same gene in related coccidia. This provides an additional challenge in developing a specific detectio...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
CONCLUSION: In cases of VL suspicion and when the parasite is not observed in the bone marrow aspiration, the proposed model could be useful in discriminating between patients with and without VL, allowing to take a therapeutic decision while awaiting the definitive diagnosis. PMID: 31466803 [PubMed - as supplied by publisher]
Source: European Journal of Internal Medicine - Category: Internal Medicine Authors: Tags: Eur J Intern Med Source Type: research
Authors: Siriwardana Y, Deepachandi B, Weliange SS, Udagedara C, Wickremarathne C, Warnasuriya W, Ranawaka RR, Kahawita I, Chandrawansa PH, Karunaweera ND Abstract Cutaneous leishmaniasis caused by a genetic variant of L. donovani is being reported from Sri Lanka since year 2001. Patients presented from different geographical locations (600 patients from North or South and a minority of cases from other foci, 2001-2013) were studied. Analysis revealed two different sociodemographic and clinical profiles of leishmaniasis in Northern and Southern Sri Lanka. Also, the same different profiles were present in these foci...
Source: Journal of Tropical Medicine - Category: Tropical Medicine Tags: J Trop Med Source Type: research
Publication date: Available online 14 August 2019Source: Veterinary ParasitologyAuthor(s): Wesley Cheung, Candace Russo, Simone Maher, Richard Malik, Jan ŠlapetaAbstractGiardia duodenalis is a common parasite in dogs in shelters where new introductions, including numerous juvenile individuals, are ongoing. A safe and effective single dose parasiticide is highly desirable for shelters experiencing disease caused by G. duodenalis (giardiosis). Secnidazole is an efficacious, low-cost medication used for the treatment of giardiosis in humans and has the advantage of requiring only a single oral dose. The aim of this stu...
Source: Veterinary Parasitology - Category: Veterinary Research Source Type: research
This study tested the hypothesis that mosquitoes from southeastern Georgia, USA may be infected with Rickettsia felis and Wolbachia, an endosymbiotic bacterium of the order Rickettsiales. Methods: Specimens of the five most common mosquito species occurring in the region were collected using gravid and light-traps and identified using morphological keys. Mosquitoes were then pooled by species, sex, trap and collection site and their DNA was extracted. Molecular methods were used to confirm mosquito identification, and presence of Wolbachia and R. felis. Results: Wolbachia DNA was detected in 90.8% of the mosquito p...
Source: Journal of Vector Borne Diseases - Category: Infectious Diseases Tags: J Vector Borne Dis Source Type: research
The objectives of this study were (i) to develop a reliable method, applicable in biomonitoring, for the rapid detection of infectious oocysts by cell culture of their sporocysts combined with qPCR (sporocyst-CC-qPCR), and (ii) to adapt this method to blue and zebra mussels experimentally contaminated by oocysts with the objective to use these organisms as sentinels of aquatic environments. Combining mechanical treatment and bead beating leads to the release of 84 ± 14% of free sporocysts. The sporocyst-CC-qPCR can detect fewer than ten infectious oocysts in water within four days (one day of contact and three days ...
Source: Applied and Environmental Microbiology - Category: Microbiology Authors: Tags: Appl Environ Microbiol Source Type: research
Non-NK group 1 innate lymphoid cells (ILC1s), mainly investigated in the mucosal areas of the intestine, are well known to contribute to anti-parasitic and anti-bacterial immune responses. Recently, our group revealed that lung ILC1s become activated during murine influenza infection, thereby contributing to viral clearance. In this context, worldwide seasonal influenza infections often result in severe disease outbreaks leading to high morbidity and mortality. Therefore, new immune interventions are urgently needed. In contrast to NK cells, the potential of non-NK ILC1s to become functionally tailored by immune modulators...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
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