Ultrasound evoke ion channels in caenorhabditis elegans by mechanical effects

Background, Motivation and Objective: As a non-invasive method, ultrasound can pass through the intact skull and activate deep brain neurons, gaining increasing attention. Fundamental mechanisms of ultrasound neuro-modulation, however, have not been elucidated clearly. The nematode Caenorhabditis elegans (C. elegans) is an excellent model organism and has been widely used in the neurobiology research. Our previous work has shown that mechanical effects of the ultrasound enable to initiate reversal behaviour and activate ASH neurons of C.

Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - January 22, 2019 Category: Neurology Authors: W. Zhou, X. Wang, L. Niu, L. Meng, H. Zheng Source Type: research